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| 1 |  |  |  |  |  |  | package WebService::UMLSKS::Similarity; | 
| 2 |  |  |  |  |  |  |  | 
| 3 | 1 |  |  | 1 |  | 25176 | use warnings; | 
|  | 1 |  |  |  |  | 4 |  | 
|  | 1 |  |  |  |  | 30 |  | 
| 4 | 1 |  |  | 1 |  | 6 | use strict; | 
|  | 1 |  |  |  |  | 2 |  | 
|  | 1 |  |  |  |  | 38 |  | 
| 5 | 1 |  |  | 1 |  | 458 | use Log::Message::Simple qw[msg error debug]; | 
|  | 0 |  |  |  |  |  |  | 
|  | 0 |  |  |  |  |  |  | 
| 6 |  |  |  |  |  |  |  | 
| 7 |  |  |  |  |  |  | no warnings qw/redefine/; | 
| 8 |  |  |  |  |  |  |  | 
| 9 |  |  |  |  |  |  | =head1 NAME | 
| 10 |  |  |  |  |  |  |  | 
| 11 |  |  |  |  |  |  | WebService::UMLSKS::Similarity - access the Unified Medical Language System (UMLS) via Webservices | 
| 12 |  |  |  |  |  |  |  | 
| 13 |  |  |  |  |  |  | =head1 VERSION | 
| 14 |  |  |  |  |  |  |  | 
| 15 |  |  |  |  |  |  | Version 0.23 | 
| 16 |  |  |  |  |  |  |  | 
| 17 |  |  |  |  |  |  | =cut | 
| 18 |  |  |  |  |  |  |  | 
| 19 |  |  |  |  |  |  | our $VERSION = '0.23'; | 
| 20 |  |  |  |  |  |  |  | 
| 21 |  |  |  |  |  |  | =head1 SYNOPSIS | 
| 22 |  |  |  |  |  |  |  | 
| 23 |  |  |  |  |  |  | =head2 Basic Usage | 
| 24 |  |  |  |  |  |  |  | 
| 25 |  |  |  |  |  |  | use WebService::UMLS::Similarity; | 
| 26 |  |  |  |  |  |  | # Creating object of similarity with default constructor. | 
| 27 |  |  |  |  |  |  | my $similarity1 = WebService::UMLS::Similarity->new(); | 
| 28 |  |  |  |  |  |  |  | 
| 29 |  |  |  |  |  |  | # Creating object of Similarity by providing Configuration parameters. | 
| 30 |  |  |  |  |  |  | my @source_list = ("SNOMEDCT", "MSH"); | 
| 31 |  |  |  |  |  |  | my @relation_list = ("PAR", "CHD","RB", "RN") ; | 
| 32 |  |  |  |  |  |  | my $similarity2 = WebService::UMLS::Similarity->new({"sources" =>  \@source_list,"rels"   =>  \@relation_list }	); | 
| 33 |  |  |  |  |  |  |  | 
| 34 |  |  |  |  |  |  | # Creating object of Similarity by providing Cinfiguration file path and name. | 
| 35 |  |  |  |  |  |  | my $similarity3 = WebService::UMLS::Similarity-> | 
| 36 |  |  |  |  |  |  | new({"config" => "/home/../config"}); | 
| 37 |  |  |  |  |  |  |  | 
| 38 |  |  |  |  |  |  | Format of configuaration file | 
| 39 |  |  |  |  |  |  |  | 
| 40 |  |  |  |  |  |  | The configuaration fie accepted by the module should be in the fillowing format | 
| 41 |  |  |  |  |  |  |  | 
| 42 |  |  |  |  |  |  | SAB :: include SNOMEDCT,MSH | 
| 43 |  |  |  |  |  |  | REL :: include PAR,RB | 
| 44 |  |  |  |  |  |  | DIR :: include U,H | 
| 45 |  |  |  |  |  |  | RELA :: include RB-has_part | 
| 46 |  |  |  |  |  |  |  | 
| 47 |  |  |  |  |  |  | Here, SAB is the sources and REL is relations you want to include in | 
| 48 |  |  |  |  |  |  | searching the UMLS. The list of sources and relations can be provided | 
| 49 |  |  |  |  |  |  | seperated by comma. Some UMLS sources are :SNOMEDCT,MSH,UWDA,CSP,FMA,NCI | 
| 50 |  |  |  |  |  |  |  | 
| 51 |  |  |  |  |  |  | =head1 DESCRIPTION | 
| 52 |  |  |  |  |  |  |  | 
| 53 |  |  |  |  |  |  | This module creates a new instance of Similarity module and while creating the | 
| 54 |  |  |  |  |  |  | instance sets all the configuration parameters which are used in rest of the module. | 
| 55 |  |  |  |  |  |  | User can provide the configuration parameters by directly passing them to the | 
| 56 |  |  |  |  |  |  | constructor using a hash of parameters with 'sources' and 'rels' options | 
| 57 |  |  |  |  |  |  | or user can provide directly the configuration file path in the constructor using | 
| 58 |  |  |  |  |  |  | 'config' option. If the user does not specify any configuartion parameters, | 
| 59 |  |  |  |  |  |  | defualt parameters are used.  'SNOMEDCT' is the deafult source used and 'PAR|CHD' | 
| 60 |  |  |  |  |  |  | are the default relations used. | 
| 61 |  |  |  |  |  |  |  | 
| 62 |  |  |  |  |  |  | =head1 SUBROUTINES | 
| 63 |  |  |  |  |  |  |  | 
| 64 |  |  |  |  |  |  | =head2 new | 
| 65 |  |  |  |  |  |  |  | 
| 66 |  |  |  |  |  |  | This sub creates a new object of Display by taking in optional configuaration | 
| 67 |  |  |  |  |  |  | parameters. | 
| 68 |  |  |  |  |  |  |  | 
| 69 |  |  |  |  |  |  | =cut | 
| 70 |  |  |  |  |  |  |  | 
| 71 |  |  |  |  |  |  | sub new { | 
| 72 |  |  |  |  |  |  |  | 
| 73 |  |  |  |  |  |  | my $class  = shift; | 
| 74 |  |  |  |  |  |  | my $params = shift; | 
| 75 |  |  |  |  |  |  |  | 
| 76 |  |  |  |  |  |  | my @s_array = ("SNOMEDCT"); | 
| 77 |  |  |  |  |  |  | my @r_array = ("PAR"); | 
| 78 |  |  |  |  |  |  | my @d_array = ("U"); | 
| 79 |  |  |  |  |  |  | my @a_array = (); | 
| 80 |  |  |  |  |  |  |  | 
| 81 |  |  |  |  |  |  | my %ConfigurationParameters = ( | 
| 82 |  |  |  |  |  |  | "SAB", \@s_array, "REL",  \@r_array, | 
| 83 |  |  |  |  |  |  | "DIR", \@d_array, "RELA", \@a_array | 
| 84 |  |  |  |  |  |  | ); | 
| 85 |  |  |  |  |  |  | my $self = \%ConfigurationParameters; | 
| 86 |  |  |  |  |  |  |  | 
| 87 |  |  |  |  |  |  | bless( $self, $class ); | 
| 88 |  |  |  |  |  |  |  | 
| 89 |  |  |  |  |  |  | # call initialiseParameters only if parameters are passed else use default values | 
| 90 |  |  |  |  |  |  | if ( defined $params && $params ne "" ) { | 
| 91 |  |  |  |  |  |  | $self->initialiseParameters($params); | 
| 92 |  |  |  |  |  |  |  | 
| 93 |  |  |  |  |  |  | #printhashvaluearray(\%ConfigurationParameters); | 
| 94 |  |  |  |  |  |  |  | 
| 95 |  |  |  |  |  |  | } | 
| 96 |  |  |  |  |  |  |  | 
| 97 |  |  |  |  |  |  | return $self; | 
| 98 |  |  |  |  |  |  | } | 
| 99 |  |  |  |  |  |  |  | 
| 100 |  |  |  |  |  |  | =head2 initialiseParameters | 
| 101 |  |  |  |  |  |  |  | 
| 102 |  |  |  |  |  |  | This subroutine sets the configuaration parameters hash | 
| 103 |  |  |  |  |  |  | which are then used in rest of the module. | 
| 104 |  |  |  |  |  |  |  | 
| 105 |  |  |  |  |  |  | =cut | 
| 106 |  |  |  |  |  |  |  | 
| 107 |  |  |  |  |  |  | sub initialiseParameters { | 
| 108 |  |  |  |  |  |  |  | 
| 109 |  |  |  |  |  |  | my $self   = shift; | 
| 110 |  |  |  |  |  |  | my $params = shift; | 
| 111 |  |  |  |  |  |  |  | 
| 112 |  |  |  |  |  |  | # set the hash to default values | 
| 113 |  |  |  |  |  |  |  | 
| 114 |  |  |  |  |  |  | if ( !defined $params || !ref $params ) { | 
| 115 |  |  |  |  |  |  |  | 
| 116 |  |  |  |  |  |  | #return; | 
| 117 |  |  |  |  |  |  | print "\nUndefined parameter reference"; | 
| 118 |  |  |  |  |  |  | } | 
| 119 |  |  |  |  |  |  |  | 
| 120 |  |  |  |  |  |  | my $file_path_name = $params->{'config'}; | 
| 121 |  |  |  |  |  |  |  | 
| 122 |  |  |  |  |  |  | my @source_list; | 
| 123 |  |  |  |  |  |  | my @relation_list; | 
| 124 |  |  |  |  |  |  | my @direction_list; | 
| 125 |  |  |  |  |  |  | if ( defined $params->{'sources'} ) { | 
| 126 |  |  |  |  |  |  | @source_list = @{ $params->{'sources'} }; | 
| 127 |  |  |  |  |  |  | } | 
| 128 |  |  |  |  |  |  | if ( defined $params->{'rels'} ) { | 
| 129 |  |  |  |  |  |  | @relation_list = @{ $params->{'rels'} }; | 
| 130 |  |  |  |  |  |  | } | 
| 131 |  |  |  |  |  |  | if ( defined $params->{'dirs'} ) { | 
| 132 |  |  |  |  |  |  | @direction_list = @{ $params->{'dirs'} }; | 
| 133 |  |  |  |  |  |  | } | 
| 134 |  |  |  |  |  |  |  | 
| 135 |  |  |  |  |  |  | my $r = 0; | 
| 136 |  |  |  |  |  |  | my $d = 0; | 
| 137 |  |  |  |  |  |  | #print "\n *****file path name: $file_path_name"; | 
| 138 |  |  |  |  |  |  |  | 
| 139 |  |  |  |  |  |  | if ( defined $file_path_name && $file_path_name ne "" ) { | 
| 140 |  |  |  |  |  |  |  | 
| 141 |  |  |  |  |  |  | my $pflag = 0; | 
| 142 |  |  |  |  |  |  | my $dflag = 1; | 
| 143 |  |  |  |  |  |  |  | 
| 144 |  |  |  |  |  |  | # If user has provided a configuration file | 
| 145 |  |  |  |  |  |  | open( CONFIG, $file_path_name ) | 
| 146 |  |  |  |  |  |  | or die("Error: cannot open configuration file '$file_path_name'\n"); | 
| 147 |  |  |  |  |  |  |  | 
| 148 |  |  |  |  |  |  | my @parameters = ; | 
| 149 |  |  |  |  |  |  |  | 
| 150 |  |  |  |  |  |  | for my $p ( 0 .. $#parameters ) { | 
| 151 |  |  |  |  |  |  |  | 
| 152 |  |  |  |  |  |  | #	print "\n $param"; | 
| 153 |  |  |  |  |  |  |  | 
| 154 |  |  |  |  |  |  | $parameters[$p] =~ /\s*(.*)\s*::\s*(.*?) (.*?)$/; | 
| 155 |  |  |  |  |  |  | msg("\n $1 \t $2 \t $3"); | 
| 156 |  |  |  |  |  |  | my $parameter_name  = $1; | 
| 157 |  |  |  |  |  |  | my $flag            = $2; | 
| 158 |  |  |  |  |  |  | my $parameter_value = $3; | 
| 159 |  |  |  |  |  |  | my @parameter_array = (); | 
| 160 |  |  |  |  |  |  |  | 
| 161 |  |  |  |  |  |  | $parameter_name  =~ s/\s*//g; | 
| 162 |  |  |  |  |  |  | $parameter_value =~ s/\s*//g; | 
| 163 |  |  |  |  |  |  | $flag            =~ s/\s*//g; | 
| 164 |  |  |  |  |  |  |  | 
| 165 |  |  |  |  |  |  | #my @parameter_array | 
| 166 |  |  |  |  |  |  |  | 
| 167 |  |  |  |  |  |  | if ( $parameter_name && $flag && $parameter_value ) { | 
| 168 |  |  |  |  |  |  |  | 
| 169 |  |  |  |  |  |  | # If more than one sources/relations specified, then seperate by comma | 
| 170 |  |  |  |  |  |  | if ( $parameter_value =~ /\,/ ) { | 
| 171 |  |  |  |  |  |  |  | 
| 172 |  |  |  |  |  |  | @parameter_array = split( ",", $parameter_value ); | 
| 173 |  |  |  |  |  |  | } | 
| 174 |  |  |  |  |  |  | else { | 
| 175 |  |  |  |  |  |  |  | 
| 176 |  |  |  |  |  |  | $parameter_array[0] = $parameter_value; | 
| 177 |  |  |  |  |  |  |  | 
| 178 |  |  |  |  |  |  | } | 
| 179 |  |  |  |  |  |  |  | 
| 180 |  |  |  |  |  |  | $parameter_name =~ s/\s*//g; | 
| 181 |  |  |  |  |  |  |  | 
| 182 |  |  |  |  |  |  | #chop($parameter_name); | 
| 183 |  |  |  |  |  |  |  | 
| 184 |  |  |  |  |  |  | if ( $parameter_name =~ /\bREL\b/ ) { | 
| 185 |  |  |  |  |  |  | $pflag = 1; | 
| 186 |  |  |  |  |  |  | $dflag = 0; | 
| 187 |  |  |  |  |  |  | $r = $#parameter_array; | 
| 188 |  |  |  |  |  |  | } | 
| 189 |  |  |  |  |  |  | if ( $pflag == 1 ) { | 
| 190 |  |  |  |  |  |  | if ( $parameter_name =~ /DIR/ ) { | 
| 191 |  |  |  |  |  |  | $dflag = 1; | 
| 192 |  |  |  |  |  |  | $d = $#parameter_array; | 
| 193 |  |  |  |  |  |  | } | 
| 194 |  |  |  |  |  |  | } | 
| 195 |  |  |  |  |  |  | if ( $flag =~ /\binclude\b/ ) { | 
| 196 |  |  |  |  |  |  |  | 
| 197 |  |  |  |  |  |  |  | 
| 198 |  |  |  |  |  |  | #print "\n including @parameter_array"; | 
| 199 |  |  |  |  |  |  | $self->{$parameter_name} = \@parameter_array; | 
| 200 |  |  |  |  |  |  | msg( | 
| 201 |  |  |  |  |  |  | "\n in hash $parameter_name: @{$self->{$parameter_name}}" | 
| 202 |  |  |  |  |  |  | ); | 
| 203 |  |  |  |  |  |  | } | 
| 204 |  |  |  |  |  |  | elsif ( $flag =~ /\bexclude\b/ ) { | 
| 205 |  |  |  |  |  |  |  | 
| 206 |  |  |  |  |  |  | # Dont do anything for now | 
| 207 |  |  |  |  |  |  | print | 
| 208 |  |  |  |  |  |  | "\n Invalid configurations: does not handle exclude yet\n"; | 
| 209 |  |  |  |  |  |  | print | 
| 210 |  |  |  |  |  |  | "\nPlease specify valid configuaration file by refering to the documentation\n"; | 
| 211 |  |  |  |  |  |  | exit; | 
| 212 |  |  |  |  |  |  |  | 
| 213 |  |  |  |  |  |  | } | 
| 214 |  |  |  |  |  |  | else { | 
| 215 |  |  |  |  |  |  | print | 
| 216 |  |  |  |  |  |  | "\n Invalid configurations, may be forgot to have 'include' keyword\n"; | 
| 217 |  |  |  |  |  |  | print | 
| 218 |  |  |  |  |  |  | "\nPlease specify valid configuaration file by refering to the documentation\n"; | 
| 219 |  |  |  |  |  |  | exit; | 
| 220 |  |  |  |  |  |  | } | 
| 221 |  |  |  |  |  |  | } | 
| 222 |  |  |  |  |  |  | else | 
| 223 |  |  |  |  |  |  |  | 
| 224 |  |  |  |  |  |  | { | 
| 225 |  |  |  |  |  |  | print "\n Invalid configurations\n"; | 
| 226 |  |  |  |  |  |  | print | 
| 227 |  |  |  |  |  |  | "\nPlease specify valid configuaration file by refering to the documentation\n"; | 
| 228 |  |  |  |  |  |  | exit; | 
| 229 |  |  |  |  |  |  | } | 
| 230 |  |  |  |  |  |  |  | 
| 231 |  |  |  |  |  |  | } | 
| 232 |  |  |  |  |  |  |  | 
| 233 |  |  |  |  |  |  |  | 
| 234 |  |  |  |  |  |  | if ( $dflag == 0 ) { | 
| 235 |  |  |  |  |  |  | print | 
| 236 |  |  |  |  |  |  | "\nIf relations are specified, it is necessay to specify directions for them"; | 
| 237 |  |  |  |  |  |  | print | 
| 238 |  |  |  |  |  |  | "\nPlease specify valid configuaration file by refering to the documentation\n"; | 
| 239 |  |  |  |  |  |  | exit; | 
| 240 |  |  |  |  |  |  | } | 
| 241 |  |  |  |  |  |  |  | 
| 242 |  |  |  |  |  |  |  | 
| 243 |  |  |  |  |  |  | if($r != $d) | 
| 244 |  |  |  |  |  |  | { | 
| 245 |  |  |  |  |  |  | print | 
| 246 |  |  |  |  |  |  | "\nEach relation must have a corresponding direction in the configuaration"; | 
| 247 |  |  |  |  |  |  | print | 
| 248 |  |  |  |  |  |  | "\nPlease specify valid configuaration file by refering to the documentation\n"; | 
| 249 |  |  |  |  |  |  | exit; | 
| 250 |  |  |  |  |  |  |  | 
| 251 |  |  |  |  |  |  | } | 
| 252 |  |  |  |  |  |  |  | 
| 253 |  |  |  |  |  |  |  | 
| 254 |  |  |  |  |  |  |  | 
| 255 |  |  |  |  |  |  | } | 
| 256 |  |  |  |  |  |  | else { | 
| 257 |  |  |  |  |  |  |  | 
| 258 |  |  |  |  |  |  | # If user has not provided a configuration file but has directly | 
| 259 |  |  |  |  |  |  | # provided the configuration option in params hash | 
| 260 |  |  |  |  |  |  |  | 
| 261 |  |  |  |  |  |  | # if no configuration file is specified | 
| 262 |  |  |  |  |  |  | # if configuration parameters are set using hash as parameter | 
| 263 |  |  |  |  |  |  |  | 
| 264 |  |  |  |  |  |  | if (   !defined $file_path_name | 
| 265 |  |  |  |  |  |  | && @source_list | 
| 266 |  |  |  |  |  |  | && @relation_list | 
| 267 |  |  |  |  |  |  | && @direction_list ) | 
| 268 |  |  |  |  |  |  | { | 
| 269 |  |  |  |  |  |  |  | 
| 270 |  |  |  |  |  |  | $self->{"SAB"} = \@source_list; | 
| 271 |  |  |  |  |  |  | $self->{"REL"} = \@relation_list; | 
| 272 |  |  |  |  |  |  | $self->{"DIR"} = \@direction_list; | 
| 273 |  |  |  |  |  |  | } | 
| 274 |  |  |  |  |  |  |  | 
| 275 |  |  |  |  |  |  | else { | 
| 276 |  |  |  |  |  |  |  | 
| 277 |  |  |  |  |  |  | if (@source_list) { | 
| 278 |  |  |  |  |  |  | $self->{"SAB"} = \@source_list; | 
| 279 |  |  |  |  |  |  | } | 
| 280 |  |  |  |  |  |  | if (@relation_list) { | 
| 281 |  |  |  |  |  |  | $self->{"REL"} = \@relation_list; | 
| 282 |  |  |  |  |  |  | } | 
| 283 |  |  |  |  |  |  | if (@direction_list) { | 
| 284 |  |  |  |  |  |  | $self->{"DIR"} = \@direction_list; | 
| 285 |  |  |  |  |  |  | } | 
| 286 |  |  |  |  |  |  |  | 
| 287 |  |  |  |  |  |  | } | 
| 288 |  |  |  |  |  |  |  | 
| 289 |  |  |  |  |  |  | #if(!defined $file_path_name && !@source_list && !@relation_list) | 
| 290 |  |  |  |  |  |  | #{ | 
| 291 |  |  |  |  |  |  | #	# nothing is specified , then use default values | 
| 292 |  |  |  |  |  |  |  | 
| 293 |  |  |  |  |  |  | #} | 
| 294 |  |  |  |  |  |  | } | 
| 295 |  |  |  |  |  |  |  | 
| 296 |  |  |  |  |  |  | } | 
| 297 |  |  |  |  |  |  |  | 
| 298 |  |  |  |  |  |  | #-------------------------------PERLDOC STARTS HERE------------------------------------------------------------- | 
| 299 |  |  |  |  |  |  |  | 
| 300 |  |  |  |  |  |  | =head1 SEE ALSO | 
| 301 |  |  |  |  |  |  |  | 
| 302 |  |  |  |  |  |  | ValidateTerm.pm  GetUserData.pm   ConnectUMLS.pm  ws-getUMLSInfo.pl ws-getAllowablePath.pl | 
| 303 |  |  |  |  |  |  |  | 
| 304 |  |  |  |  |  |  | =cut | 
| 305 |  |  |  |  |  |  |  | 
| 306 |  |  |  |  |  |  | =head1 AUTHORS | 
| 307 |  |  |  |  |  |  |  | 
| 308 |  |  |  |  |  |  | Mugdha Choudhari,             University of Minnesota Duluth | 
| 309 |  |  |  |  |  |  | Echou0130 at d.umn.eduE | 
| 310 |  |  |  |  |  |  |  | 
| 311 |  |  |  |  |  |  | Ted Pedersen,                University of Minnesota Duluth | 
| 312 |  |  |  |  |  |  | Etpederse at d.umn.eduE | 
| 313 |  |  |  |  |  |  |  | 
| 314 |  |  |  |  |  |  |  | 
| 315 |  |  |  |  |  |  |  | 
| 316 |  |  |  |  |  |  |  | 
| 317 |  |  |  |  |  |  | =head1 COPYRIGHT | 
| 318 |  |  |  |  |  |  |  | 
| 319 |  |  |  |  |  |  | Copyright (C) 2011, Mugdha Choudhari, Ted Pedersen | 
| 320 |  |  |  |  |  |  |  | 
| 321 |  |  |  |  |  |  | This program is free software; you can redistribute it and/or modify | 
| 322 |  |  |  |  |  |  | it under the terms of the GNU General Public License as published by | 
| 323 |  |  |  |  |  |  | the Free Software Foundation; either version 2 of the License, or (at | 
| 324 |  |  |  |  |  |  | your option) any later version. | 
| 325 |  |  |  |  |  |  |  | 
| 326 |  |  |  |  |  |  | This program is distributed in the hope that it will be useful, but | 
| 327 |  |  |  |  |  |  | WITHOUT ANY WARRANTY; without even the implied warranty of | 
| 328 |  |  |  |  |  |  | MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the GNU | 
| 329 |  |  |  |  |  |  | General Public License for more details. | 
| 330 |  |  |  |  |  |  |  | 
| 331 |  |  |  |  |  |  | You should have received a copy of the GNU General Public License | 
| 332 |  |  |  |  |  |  | along with this program; if not, write to | 
| 333 |  |  |  |  |  |  | The Free Software Foundation, Inc., | 
| 334 |  |  |  |  |  |  | 59 Temple Place - Suite 330, | 
| 335 |  |  |  |  |  |  | Boston, MA  02111-1307, USA. | 
| 336 |  |  |  |  |  |  |  | 
| 337 |  |  |  |  |  |  | =cut | 
| 338 |  |  |  |  |  |  |  | 
| 339 |  |  |  |  |  |  | #---------------------------------PERLDOC ENDS HERE--------------------------------------------------------------- | 
| 340 |  |  |  |  |  |  |  | 
| 341 |  |  |  |  |  |  | 1;    # End of WebService::UMLS::Similarity |