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package PomBase::Chobo::ParseOBO; |
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=head1 NAME |
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PomBase::Chobo::ParseOBO - Parse the bits of an OBO file needed for |
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loading Chado |
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=head1 SYNOPSIS |
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=head1 AUTHOR |
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Kim Rutherford C<< >> |
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=head1 BUGS |
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Please report any bugs or feature requests to C. |
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=head1 SUPPORT |
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You can find documentation for this module with the perldoc command. |
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perldoc PomBase::Chobo::ParseOBO |
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=over 4 |
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=back |
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=head1 COPYRIGHT & LICENSE |
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30
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Copyright 2012 Kim Rutherford, all rights reserved. |
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32
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This program is free software; you can redistribute it and/or modify it |
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under the same terms as Perl itself. |
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34
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35
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=head1 FUNCTIONS |
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36
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37
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=cut |
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38
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39
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our $VERSION = '0.041'; # VERSION |
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40
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41
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5
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5
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637512
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use Mouse; |
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5
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137570
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5
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27
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42
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5
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5
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5591
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use FileHandle; |
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5
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45126
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5
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40
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43
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44
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5
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5
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5208
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use PomBase::Chobo::OntologyData; |
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5
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63
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5
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10742
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45
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46
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sub die_line |
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47
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{ |
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48
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0
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0
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0
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0
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my $filename = shift; |
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49
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0
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0
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my $linenum = shift; |
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50
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0
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0
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my $message = shift; |
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51
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52
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0
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0
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die "$filename:$linenum:$message\n"; |
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53
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} |
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54
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55
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sub _finish_stanza |
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56
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{ |
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57
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81
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81
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127
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my $filename = shift; |
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58
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81
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124
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my $current = shift; |
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59
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81
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119
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my $terms_ref = shift; |
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60
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81
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109
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my $metadata_ref = shift; |
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61
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62
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81
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50
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66
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251
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if ($current->{is_obsolete} && $current->{is_relationshiptype}) { |
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63
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0
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0
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return; |
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64
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} |
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65
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66
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81
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50
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213
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if (!defined $current->{name}) { |
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67
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0
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0
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warn "term without a name tag ignored: ", $current->{id}, "\n"; |
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68
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0
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0
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return; |
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69
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} |
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70
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71
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81
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50
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195
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if (!defined $current->{id}) { |
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72
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0
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0
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die_line $filename, $current->{line}, "stanza has no id\n"; |
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73
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0
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0
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return; |
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74
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} |
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75
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76
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81
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100
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275
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if ($current->{id} !~ /:/) { |
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77
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# try to find a sensible ID if the ID looks like a name ("id: output_of") |
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78
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12
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100
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36
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if ($current->{xref}) { |
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79
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6
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11
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for my $xref (@{$current->{xref}}) { |
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6
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58
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80
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6
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100
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26
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if ($xref =~ /^RO:/) { |
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81
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2
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7
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$current->{id} = $xref; |
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82
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goto ID_FIXED |
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83
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2
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23
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} |
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84
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} |
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85
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86
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4
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8
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for my $xref (@{$current->{xref}}) { |
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4
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9
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87
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4
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50
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14
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if ($xref =~ /^BFO:/) { |
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88
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0
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0
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$current->{id} = $xref; |
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89
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goto ID_FIXED |
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90
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0
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0
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} |
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91
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} |
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92
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} |
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93
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} |
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94
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95
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ID_FIXED: |
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96
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81
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100
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200
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if ($current->{is_obsolete}) { |
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97
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6
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19
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delete $current->{alt_id}; |
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98
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} |
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99
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100
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81
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171
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$current->{metadata} = $metadata_ref; |
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101
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81
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181
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$current->{source_file} = $filename; |
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102
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81
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100
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454
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$current->{relationship} //= []; |
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103
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104
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81
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128
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my $namespace_from_metadata = 0; |
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105
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106
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81
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100
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176
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if (!defined $current->{namespace}) { |
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107
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$current->{namespace} = |
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108
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$metadata_ref->{'default-namespace'} // |
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109
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$metadata_ref->{'ontology'} // |
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110
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40
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66
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162
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$current->{source_file} . '::' . $current->{id} =~ s/:.*//r; |
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33
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111
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112
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40
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100
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137
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if ($current->{namespace} eq 'ro') { |
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113
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4
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10
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$current->{namespace} = 'relations'; |
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114
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} |
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115
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116
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40
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61
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$namespace_from_metadata = 1; |
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117
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} |
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118
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119
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81
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100
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171
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if ($current->{is_a}) { |
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120
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map { |
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121
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55
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77
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push @{$current->{relationship}}, |
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55
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263
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122
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{ |
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123
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'relationship_name' => 'is_a', |
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124
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'other_term' => $_, |
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125
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}; |
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126
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48
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67
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} @{$current->{is_a}}; |
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48
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137
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127
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128
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48
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121
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delete $current->{is_a}; |
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129
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} |
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130
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131
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81
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100
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175
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if ($current->{synonym}) { |
|
132
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37
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76
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my %seen_synonyms = (); |
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133
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134
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$current->{synonym} = [ |
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135
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map { |
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136
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137
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66
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147
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my $seen_synonym = $seen_synonyms{$_->{synonym}}; |
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138
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66
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100
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66
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160
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if ($seen_synonym && lc $seen_synonym->{scope} eq 'exact') { |
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139
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# keep it |
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140
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} else { |
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141
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63
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228
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$seen_synonyms{$_->{synonym}} = $_; |
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142
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} |
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143
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37
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76
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} @{$current->{synonym}} |
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37
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88
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144
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]; |
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145
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146
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37
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329
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$current->{synonym} = [sort { $a->{synonym} cmp $b->{synonym} } values %seen_synonyms]; |
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34
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104
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147
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} |
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148
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149
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81
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237
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my $options = { namespace_from_metadata => $namespace_from_metadata }; |
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150
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151
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81
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411
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my $new_term = PomBase::Chobo::OntologyTerm->make_object($current, $options); |
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152
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153
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81
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320
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push @$terms_ref, $new_term; |
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154
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} |
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155
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156
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sub fatal |
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157
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{ |
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158
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0
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0
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0
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0
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my $message = shift; |
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159
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160
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0
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0
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die "fatal: $message\n"; |
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161
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} |
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162
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163
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my %interesting_metadata = ( |
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164
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'default-namespace' => 1, |
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165
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'ontology' => 1, |
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166
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'date' => 1, |
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167
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'data-version' => 1, |
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168
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); |
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169
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170
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sub parse |
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171
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{ |
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172
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13
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13
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0
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5514
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my $self = shift; |
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173
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13
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65
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my %args = @_; |
|
174
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175
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13
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35
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my $filename = $args{filename}; |
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176
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13
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50
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46
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if (!defined $filename) { |
|
177
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0
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0
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die 'no filename passed to parse()'; |
|
178
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} |
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179
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180
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13
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31
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my $ontology_data = $args{ontology_data}; |
|
181
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13
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50
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39
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if (!defined $ontology_data) { |
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182
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0
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0
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die 'no ontology_data passed to parse()'; |
|
183
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} |
|
184
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185
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13
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30
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my %metadata = (); |
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186
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13
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23
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my @terms = (); |
|
187
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188
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13
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24
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my $current = undef; |
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189
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13
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107
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my @synonyms = (); |
|
190
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191
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13
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25
|
my %meta = (); |
|
192
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|
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|
193
|
13
|
50
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|
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|
942
|
open my $fh, '<:utf8', $filename or die "can't open $filename: $!"; |
|
194
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|
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195
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13
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43
|
my $line_number = 0;; |
|
196
|
|
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|
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|
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|
197
|
13
|
|
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|
|
777
|
while (defined (my $line = <$fh>)) { |
|
198
|
899
|
|
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|
|
1239
|
$line_number++; |
|
199
|
899
|
|
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|
|
1411
|
chomp $line; |
|
200
|
899
|
|
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|
|
1749
|
$line =~ s/![^"\n]*$//; |
|
201
|
899
|
|
|
|
|
2865
|
$line =~ s/\s+$//; |
|
202
|
899
|
|
|
|
|
1627
|
$line =~ s/^\s+//; |
|
203
|
|
|
|
|
|
|
|
|
204
|
899
|
100
|
|
|
|
2296
|
next if length $line == 0; |
|
205
|
|
|
|
|
|
|
|
|
206
|
812
|
100
|
|
|
|
1722
|
if ($line =~ /^\[(.*)\]$/) { |
|
207
|
81
|
|
|
|
|
188
|
my $stanza_type = $1; |
|
208
|
|
|
|
|
|
|
|
|
209
|
81
|
100
|
|
|
|
184
|
if (defined $current) { |
|
210
|
68
|
|
|
|
|
237
|
_finish_stanza($filename, $current, \@terms, \%metadata); |
|
211
|
|
|
|
|
|
|
} |
|
212
|
|
|
|
|
|
|
|
|
213
|
81
|
|
|
|
|
159
|
my $is_relationshiptype = 0; |
|
214
|
|
|
|
|
|
|
|
|
215
|
81
|
100
|
|
|
|
211
|
if ($stanza_type eq 'Typedef') { |
|
216
|
14
|
|
|
|
|
30
|
$is_relationshiptype = 1; |
|
217
|
|
|
|
|
|
|
} else { |
|
218
|
67
|
50
|
|
|
|
155
|
if ($stanza_type ne 'Term') { |
|
219
|
0
|
|
|
|
|
0
|
die "unknown stanza type '[$stanza_type]'\n"; |
|
220
|
|
|
|
|
|
|
} |
|
221
|
|
|
|
|
|
|
} |
|
222
|
81
|
|
|
|
|
466
|
$current = { |
|
223
|
|
|
|
|
|
|
is_relationshiptype => $is_relationshiptype, |
|
224
|
|
|
|
|
|
|
source_file_line_number => $line_number, |
|
225
|
|
|
|
|
|
|
}; |
|
226
|
|
|
|
|
|
|
} else { |
|
227
|
731
|
100
|
|
|
|
1275
|
if ($current) { |
|
228
|
622
|
|
|
|
|
1693
|
my @bits = split /: /, $line, 2; |
|
229
|
622
|
50
|
|
|
|
1434
|
if (@bits == 2) { |
|
230
|
622
|
|
|
|
|
915
|
my $field_name = $bits[0]; |
|
231
|
622
|
|
|
|
|
839
|
my $field_value = $bits[1]; |
|
232
|
|
|
|
|
|
|
|
|
233
|
|
|
|
|
|
|
# ignored for now |
|
234
|
622
|
|
|
|
|
758
|
my $modifier_string; |
|
235
|
|
|
|
|
|
|
|
|
236
|
622
|
100
|
|
|
|
1207
|
if ($field_value =~ /\}$/) { |
|
237
|
2
|
|
|
|
|
15
|
$field_value =~ s/(.*)\{(.*)\}$/$1/; |
|
238
|
2
|
|
|
|
|
6
|
$modifier_string = $2; |
|
239
|
2
|
|
|
|
|
11
|
$field_value =~ s/\s+$//; |
|
240
|
|
|
|
|
|
|
} |
|
241
|
|
|
|
|
|
|
|
|
242
|
622
|
|
|
|
|
1323
|
my $field_conf = $PomBase::Chobo::OntologyConf::field_conf{$field_name}; |
|
243
|
|
|
|
|
|
|
|
|
244
|
622
|
100
|
|
|
|
1426
|
if (defined $field_conf) { |
|
245
|
487
|
100
|
|
|
|
1012
|
if (defined $field_conf->{process}) { |
|
246
|
240
|
|
|
|
|
367
|
eval { |
|
247
|
240
|
|
|
|
|
655
|
$field_value = $field_conf->{process}->($field_value); |
|
248
|
|
|
|
|
|
|
}; |
|
249
|
240
|
50
|
|
|
|
492
|
if ($@) { |
|
250
|
0
|
|
|
|
|
0
|
warn qq(warning "$@" at $filename line $.\n); |
|
251
|
|
|
|
|
|
|
} |
|
252
|
|
|
|
|
|
|
} |
|
253
|
487
|
100
|
|
|
|
856
|
if (defined $field_value) { |
|
254
|
486
|
100
|
100
|
|
|
2057
|
if (defined $field_conf->{type} && |
|
|
|
|
66
|
|
|
|
|
|
255
|
|
|
|
|
|
|
($field_conf->{type} eq 'SINGLE' || $field_conf->{type} eq 'SINGLE_HASH')) { |
|
256
|
294
|
|
|
|
|
1740
|
$current->{$field_name} = $field_value; |
|
257
|
|
|
|
|
|
|
} else { |
|
258
|
192
|
|
|
|
|
307
|
push @{$current->{$field_name}}, $field_value; |
|
|
192
|
|
|
|
|
1715
|
|
|
259
|
|
|
|
|
|
|
} |
|
260
|
|
|
|
|
|
|
} |
|
261
|
|
|
|
|
|
|
} |
|
262
|
|
|
|
|
|
|
} else { |
|
263
|
0
|
|
|
|
|
0
|
die "can't parse line - no colon: $line\n"; |
|
264
|
|
|
|
|
|
|
} |
|
265
|
|
|
|
|
|
|
} else { |
|
266
|
|
|
|
|
|
|
# we're parsing metadata |
|
267
|
109
|
50
|
|
|
|
404
|
if ($line =~ /^(.+?):\s*(.*)/) { |
|
268
|
109
|
|
|
|
|
393
|
my ($key, $value) = ($1, $2); |
|
269
|
|
|
|
|
|
|
|
|
270
|
109
|
100
|
|
|
|
439
|
if ($interesting_metadata{$key}) { |
|
271
|
40
|
50
|
|
|
|
108
|
if (defined $metadata{$key}) { |
|
272
|
0
|
|
|
|
|
0
|
warn qq(metadata key "$key" occurs more than once in header\n); |
|
273
|
|
|
|
|
|
|
} else { |
|
274
|
40
|
|
|
|
|
183
|
$metadata{$key} = $value; |
|
275
|
|
|
|
|
|
|
} |
|
276
|
|
|
|
|
|
|
} |
|
277
|
|
|
|
|
|
|
} else { |
|
278
|
0
|
|
|
|
|
0
|
fatal "can't parse header line: $line"; |
|
279
|
|
|
|
|
|
|
} |
|
280
|
|
|
|
|
|
|
} |
|
281
|
|
|
|
|
|
|
} |
|
282
|
|
|
|
|
|
|
} |
|
283
|
|
|
|
|
|
|
|
|
284
|
13
|
50
|
|
|
|
43
|
if (defined $current) { |
|
285
|
13
|
|
|
|
|
55
|
_finish_stanza($filename, $current, \@terms, \%metadata); |
|
286
|
|
|
|
|
|
|
} |
|
287
|
|
|
|
|
|
|
|
|
288
|
13
|
50
|
|
|
|
276
|
close $fh or die "can't close $filename: $!"; |
|
289
|
|
|
|
|
|
|
|
|
290
|
13
|
|
|
|
|
28
|
eval { |
|
291
|
13
|
|
|
|
|
88
|
$ontology_data->add(metadata => \%metadata, |
|
292
|
|
|
|
|
|
|
terms => \@terms); |
|
293
|
|
|
|
|
|
|
}; |
|
294
|
13
|
50
|
|
|
|
173
|
if ($@) { |
|
295
|
0
|
|
|
|
|
|
die "failed while reading $filename: $@\n"; |
|
296
|
|
|
|
|
|
|
} |
|
297
|
|
|
|
|
|
|
} |
|
298
|
|
|
|
|
|
|
|
|
299
|
|
|
|
|
|
|
1; |