File Coverage

blib/lib/GenOO/RegionCollection/Type/DBIC.pm

Criterion	Covered	Total	%
statement	67	86	77.9
branch	7	16	43.7
condition	3	6	50.0
subroutine	24	29	82.7
pod	0	20	0.0
total	101	157	64.3

# POD documentation - main docs before the code

=head1 NAME

GenOO::RegionCollection::Type::DBIC - Class for a collection of GenOO::Region objects stored in a database.

=head1 SYNOPSIS

    # Object that corresponds to a collection of GenOO::Region objects.
    # To initialize
    my $region_collection = GenOO::RegionCollection::DB->new(
        driver      => undef,
        host        => undef,
        database    => undef,
        table       => undef,
        user        => undef,
        password    => undef,
        port        => undef,
        name        => undef,
        species     => undef,
        description => undef,
        extra       => undef,
    );


=head1 DESCRIPTION

    This class consumes the L<GenOO::RegionCollection> role.
    An instance of this class corresponds to a collection of records consuming the L<GenOO::Region>
    role.The records are stored in a database (ie MySQL, SQLite, etc) and the class offers methods
    for quering them and accessing specific characteristics (eg. longest record). Internally the class
    rests on DBIx::Class for the database access and for defining the appropriate result objects.
    Note that the columns which correspond to the required attributes of L<GenOO::Region> must exist
    in the table schema (ie. strand, rname, start, stop, copy_number)

=head1 EXAMPLES

    # Get the records contained in a specific region
    my @records = $region_collection->records_contained_in_region(1,'chr3',127726308,127792250);

    # Get the longest record
    my $longest_record = $region_collection->longest_record;

=cut

# Let the code begin...

package GenOO::RegionCollection::Type::DBIC;
$GenOO::RegionCollection::Type::DBIC::VERSION = '1.5.1';

#######################################################################
#######################   Load External modules   #####################
#######################################################################
use Modern::Perl;
use autodie;
use Moose;
use namespace::autoclean;


#######################################################################
########################   Load GenOO modules   #######################
#######################################################################
use GenOO::Data::DB::DBIC::Species::Schema;


#######################################################################
#######################   Interface attributes   ######################
#######################################################################
has 'dsn' => (
	isa      => 'Str',
	is       => 'ro',
);

has 'user' => (
	isa => 'Maybe[Str]',
	is => 'ro'
);

has 'password' => (
	isa => 'Maybe[Str]',
	is  => 'ro'
);

has 'attributes' => (
	traits    => ['Hash'],
	is        => 'ro',
	isa       => 'HashRef[Str]',
	default   => sub { {} },
);

has 'table' => (
	isa      => 'Str',
	is       => 'ro',
);

has 'records_class' => (
	is        => 'ro',
	default   => 'GenOO::Data::DB::DBIC::Species::Schema::SampleResultBase::v1',
);

has 'name' => (
	isa => 'Str',
	is => 'rw'
);

has 'species' => (
	isa => 'Str',
	is => 'rw'
);

has 'description' => (
	isa => 'Str',
	is => 'rw'
);

has 'schema' => (
	isa       => 'GenOO::Data::DB::DBIC::Species::Schema',
	is        => 'ro',
	builder   => '_init_schema',
	init_arg  => undef,
	lazy      => 1,
);

has 'resultset' => (
	is        => 'rw',
	builder   => '_init_resultset',
	init_arg  => undef,
	lazy      => 1,
);

has 'original_resultset' => (
	is        => 'rw',
	builder   => '_init_resultset',
	init_arg  => undef,
	lazy      => 1,
);

has 'longest_record' => (
	is        => 'ro',
	builder   => '_find_longest_record',
	clearer   => '_clear_longest_record',
	init_arg  => undef,
	lazy      => 1,
);

with 'GenOO::RegionCollection';

#######################################################################
########################   Interface Methods   ########################
#######################################################################
sub add_record {
	my ($self, $record) = @_;

	warn 'Method "add_record" has not been implemented yet'; # TODO
	$self->_reset;
}

sub foreach_record_do {
	my ($self, $block) = @_;

	while (my $record = $self->resultset->next) {
		last if $block->($record) eq 'break_loop'; # break the loop if the routine returns 'break_loop'
	}
}

sub foreach_record_sorted_by_location_do {
	my ($self, $block) = @_;

	my $rs = $self->resultset->search({}, {
		order_by => { -asc => ['strand', 'rname', 'start']},
	});
	while (my $record = $rs->next) {
		last if $block->($record) eq 'break_loop'; # break the loop if the routine returns 'break_loop'
	}
}

sub foreach_record_on_rname_do {
	my ($self, $rname, $block) = @_;

	my $rs = $self->resultset->search({rname => $rname});
	while (my $record = $rs->next) {
		last if $block->($record) eq 'break_loop'; # break the loop if the routine returns 'break_loop'
	}
}

sub records_count {
	my ($self) = @_;

	return $self->resultset->count || 0;
}

sub strands {
	my ($self) = @_;

	return $self->resultset->search({},{
		columns  => [ qw/strand/ ],
		distinct => 1
	})->get_column('strand')->all;
}

sub rnames_for_strand {
	my ($self, $strand) = @_;

	return $self->resultset->search({
		strand => $strand
	},{
		columns  => [ qw/strand/ ],
		distinct => 1
	})->get_column('rname')->all;
}

sub rnames_for_all_strands {
	my ($self) = @_;

	return $self->resultset->search({},{
		columns  => [ qw/rname/ ],
		distinct => 1
	})->get_column('rname')->all;;
}

sub is_empty {
	my ($self) = @_;

	if ($self->records_count > 0) {
		return 0;
	}
	else {
		return 1;
	}
}

sub is_not_empty {
	my ($self) = @_;

	return !$self->is_empty;
}

sub foreach_contained_record_do {
	my ($self, $strand, $rname, $start, $stop, $block) = @_;

	my $rs = $self->resultset->search({
		strand => $strand,
		rname  => $rname,
		start  => { '-between' => [$start, $stop] },
		stop   => { '-between' => [$start, $stop] },
	});

	while (my $record = $rs->next) {
		last if $block->($record) eq 'break_loop'; # break the loop if the routine returns 'break_loop'
	}
}

sub records_contained_in_region {
	my ($self, $strand, $rname, $start, $stop) = @_;

	return $self->resultset->search({
		strand => $strand,
		rname  => $rname,
		start  => { '-between' => [$start, $stop] },
		stop   => { '-between' => [$start, $stop] },
	})->all;
}

sub total_copy_number_for_records_contained_in_region {
	my ($self, $strand, $rname, $start, $stop) = @_;

	return $self->resultset->search({
		strand => $strand,
		rname  => $rname,
		start  => { '-between' => [$start, $stop] },
		stop   => { '-between' => [$start, $stop] },
	})->get_column('copy_number')->sum || 0;
}

sub total_copy_number {
	my ($self) = @_;

	return $self->resultset->get_column('copy_number')->sum || 0;
}

sub filter_by_length {
	my ($self, $min_length, $max_length) = @_;

	my $rs = $self->resultset->search(
		\['(stop - start + 1) BETWEEN (?+0) AND (?+0)', [dummy => $min_length], [dummy => $max_length]]
	);
	$self->resultset($rs);
}

sub filter_by_min_length {
	my ($self, $min_length) = @_;

	my $rs = $self->resultset->search(
		\['(stop - start + 1) >= (?+0)', [dummy => $min_length]]
	);
	$self->resultset($rs);
}

sub filter_by_max_length {
	my ($self, $max_length) = @_;

	my $rs = $self->resultset->search(
		\['(stop - start + 1) <= (?+0)', [dummy => $max_length]]
	);
	$self->resultset($rs);
}

sub simple_filter {
	my ($self, $col_name, $filter) = @_;
	# eg. $col_name=deletion, $filter='def'
	#     $col_name=alignment_length, $filter='>31'

	my $filtered_rs = $self->resultset;

	if ($filter eq 'def') {
		$filtered_rs = $filtered_rs->search({$col_name => {'!=', undef}});
	}
	elsif ($filter eq 'undef') {
		$filtered_rs = $filtered_rs->search({$col_name => undef});
	}
	elsif ($filter =~ /^([>=!<]{1,2})(.+)$/) {
		my $symbol = $1;
		my $value  = $2;
		$filtered_rs = $filtered_rs->search({$col_name => { $symbol => $value }});
	}
	else {
		warn "Filter $filter does not fit the guidelines.";
	}


	$self->resultset($filtered_rs);
}


#######################################################################
#########################   Private methods  ##########################
#######################################################################
sub _init_schema {
	my ($self) = @_;

	return GenOO::Data::DB::DBIC::Species::Schema->connect($self->dsn, $self->user, $self->password, $self->attributes);
}

sub _init_resultset {
	my ($self) = @_;

	return $self->schema->sample_resultset($self->records_class, $self->table);
}

sub _find_longest_record {
	my ($self) = @_;

	return $self->resultset->search({}, {
		order_by => { -desc => 'stop-start+1' },
		rows => 1,
	})->single;
}

sub _reset {
	my ($self) = @_;

	$self->_clear_longest_record;
}


#######################################################################
#######################   Deprecated methods  #########################
#######################################################################
sub foreach_overlapping_record_do {
	my ($self, @args) = @_;

	warn 'Deprecated use of "foreach_overlapping_record_do".'.
	     'Using "foreach_contained_record_do" instead.' . "\n";
	$self->foreach_contained_record_do(@args);
}

sub records_overlapping_region {
	my ($self, @args) = @_;

	warn 'Deprecated use of "records_overlapping_region".'.
	     'Using "records_contained_in_region" instead.' . "\n";
	$self->records_contained_in_region(@args);
}


__PACKAGE__->meta->make_immutable;

1;