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# BioPerl module for Bio::Phenotype::Correlate |
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# |
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# Please direct questions and support issues to |
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# Cared for by Christian M. Zmasek or |
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# |
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# (c) Christian M. Zmasek, czmasek-at-burnham.org, 2002. |
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# (c) GNF, Genomics Institute of the Novartis Research Foundation, 2002. |
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# |
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# You may distribute this module under the same terms as perl itself. |
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# Refer to the Perl Artistic License (see the license accompanying this |
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# software package, or see http://www.perl.com/language/misc/Artistic.html) |
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# for the terms under which you may use, modify, and redistribute this module. |
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# |
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# THIS PACKAGE IS PROVIDED "AS IS" AND WITHOUT ANY EXPRESS OR IMPLIED |
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# WARRANTIES, INCLUDING, WITHOUT LIMITATION, THE IMPLIED WARRANTIES OF |
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# MERCHANTIBILITY AND FITNESS FOR A PARTICULAR PURPOSE. |
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# |
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# You may distribute this module under the same terms as perl itself |
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# POD documentation - main docs before the code |
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=head1 NAME |
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Bio::Phenotype::Correlate - Representation of a correlating phenotype in a given species |
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=head1 SYNOPSIS |
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use Bio::Phenotype::Correlate; |
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$co = Bio::Phenotype::Correlate->new( -name => "4(Tas1r3)", |
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-description => "mouse correlate of human phenotype MIM 605865", |
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-species => $mouse, |
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-type => "homolog", |
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-comment => "type=homolog is putative" ); |
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print $co->name(); |
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print $co->description(); |
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print $co->species()->binomial(); |
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print $co->type(); |
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print $co->comment(); |
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print $co->to_string(); |
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=head1 DESCRIPTION |
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This class models correlating phenotypes. |
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Its creation was inspired by the OMIM database where many human phenotypes |
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have a correlating mouse phenotype. Therefore, this class is intended |
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to be used together with a phenotype class. |
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=head1 FEEDBACK |
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=head2 Mailing Lists |
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User feedback is an integral part of the evolution of this and other |
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Bioperl modules. Send your comments and suggestions preferably to one |
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of the Bioperl mailing lists. Your participation is much appreciated. |
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bioperl-l@bioperl.org - General discussion |
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http://bioperl.org/wiki/Mailing_lists - About the mailing lists |
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=head2 Support |
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Please direct usage questions or support issues to the mailing list: |
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I |
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rather than to the module maintainer directly. Many experienced and |
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reponsive experts will be able look at the problem and quickly |
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address it. Please include a thorough description of the problem |
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with code and data examples if at all possible. |
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=head2 Reporting Bugs |
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Report bugs to the Bioperl bug tracking system to help us keep track |
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the bugs and their resolution. Bug reports can be submitted via the |
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web: |
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https://github.com/bioperl/bioperl-live/issues |
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=head1 AUTHOR |
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Christian M. Zmasek |
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Email: czmasek-at-burnham.org or cmzmasek@yahoo.com |
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WWW: http://monochrome-effect.net/ |
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Address: |
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Genomics Institute of the Novartis Research Foundation |
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10675 John Jay Hopkins Drive |
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San Diego, CA 92121 |
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=head1 APPENDIX |
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The rest of the documentation details each of the object |
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methods. |
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=cut |
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# Let the code begin... |
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package Bio::Phenotype::Correlate; |
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use strict; |
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use Bio::Species; |
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use base qw(Bio::Root::Root); |
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=head2 new |
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Title : new |
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Usage : $co = Bio::Phenotype::Correlate->new( -name => "4(Tas1r3)", |
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-description => "mouse correlate of human phenotype MIM 605865", |
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-species => $mouse, |
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-type => "homolog", |
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-comment => "type=homolog is putative" ); |
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Function: Creates a new Correlate object. |
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Returns : A new Correlate object. |
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Args : -name => a name or id |
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-description => a description |
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-species => the species of this correlating phenotype [Bio::Species] |
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-type => the type of correlation |
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-comment => a comment |
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=cut |
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sub new { |
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my( $class, @args ) = @_; |
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my $self = $class->SUPER::new( @args ); |
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my ( $name, $desc, $species, $type, $comment ) |
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= $self->_rearrange( [ qw( NAME |
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DESCRIPTION |
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SPECIES |
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TYPE |
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COMMENT ) ], @args ); |
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$self->init(); |
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$name && $self->name( $name ); |
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$desc && $self->description( $desc ); |
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$species && $self->species( $species ); |
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$type && $self->type( $type ); |
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$comment && $self->comment( $comment ); |
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return $self; |
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} # new |
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=head2 init |
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Title : init() |
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Usage : $co->init(); |
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Function: Initializes this Correlate to all "". |
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Returns : |
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Args : |
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=cut |
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sub init { |
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my( $self ) = @_; |
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$self->name( "" ); |
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$self->description( "" ); |
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my $species = Bio::Species->new(); |
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$species->classification( qw( species Undetermined ) ); |
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$self->species( $species ); |
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$self->type( "" ); |
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$self->comment( "" ); |
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} # init |
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=head2 name |
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Title : name |
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Usage : $co->name( "4(Tas1r3)" ); |
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or |
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print $co->name(); |
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Function: Set/get for the name or id of this Correlate. |
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Returns : The name or id of this Correlate. |
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Args : The name or id of this Correlate (optional). |
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=cut |
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sub name { |
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my ( $self, $value ) = @_; |
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if ( defined $value ) { |
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$self->{ "_name" } = $value; |
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} |
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return $self->{ "_name" }; |
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} # name |
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=head2 description |
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Title : description |
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Usage : $co->description( "mouse correlate of human phenotype MIM 03923" ); |
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or |
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print $co->description(); |
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Function: Set/get for the description of this Correlate. |
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Returns : A description of this Correlate. |
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Args : A description of this Correlate (optional). |
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224
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=cut |
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sub description { |
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my ( $self, $value ) = @_; |
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if ( defined $value ) { |
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$self->{ "_description" } = $value; |
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} |
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233
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return $self->{ "_description" }; |
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235
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} # description |
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237
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238
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239
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240
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=head2 species |
241
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242
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Title : species |
243
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Usage : $co->species( $species ); |
244
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or |
245
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$species = $co->species(); |
246
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Function: Set/get for the species of this Correlate. |
247
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Returns : The Bio::Species of this Correlate [Bio::Species]. |
248
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Args : The Bio::Species of this Correlate [Bio::Species] (optional). |
249
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250
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=cut |
251
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252
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sub species { |
253
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254
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15
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15
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1
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35
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my ( $self, $value ) = @_; |
255
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256
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15
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100
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43
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if ( defined $value ) { |
257
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11
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40
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$self->_check_ref_type( $value, "Bio::Species" ); |
258
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11
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28
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$self->{ "_species" } = $value; |
259
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} |
260
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261
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15
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44
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return $self->{ "_species" }; |
262
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263
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} # species |
264
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265
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266
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267
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268
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=head2 type |
269
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270
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Title : type |
271
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Usage : $co->type( "homolog" ); |
272
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or |
273
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print $co->type(); |
274
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Function: Set/get for the type of this Correlate. |
275
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Returns : The type of this Correlate. |
276
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Args : The type of this Correlate (optional). |
277
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278
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=cut |
279
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280
|
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sub type { |
281
|
17
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17
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1
|
43
|
my ( $self, $value ) = @_; |
282
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283
|
17
|
100
|
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|
56
|
if ( defined $value ) { |
284
|
12
|
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|
29
|
$self->{ "_type" } = $value; |
285
|
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} |
286
|
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287
|
17
|
|
|
|
|
44
|
return $self->{ "_type" }; |
288
|
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289
|
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|
} # type |
290
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291
|
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292
|
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293
|
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294
|
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|
=head2 comment |
295
|
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296
|
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|
Title : comment |
297
|
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|
|
Usage : $co->comment( "doubtful" ); |
298
|
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|
or |
299
|
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|
|
print $co->comment(); |
300
|
|
|
|
|
|
|
Function: Set/get for an arbitrary comment about this Correlate. |
301
|
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|
|
Returns : A comment. |
302
|
|
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|
|
|
|
Args : A comment (optional). |
303
|
|
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|
304
|
|
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|
|
|
|
=cut |
305
|
|
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|
|
|
|
|
306
|
|
|
|
|
|
|
sub comment { |
307
|
13
|
|
|
13
|
1
|
41
|
my ( $self, $value ) = @_; |
308
|
|
|
|
|
|
|
|
309
|
13
|
100
|
|
|
|
33
|
if ( defined $value ) { |
310
|
10
|
|
|
|
|
22
|
$self->{ "_comment" } = $value; |
311
|
|
|
|
|
|
|
} |
312
|
|
|
|
|
|
|
|
313
|
13
|
|
|
|
|
35
|
return $self->{ "_comment" }; |
314
|
|
|
|
|
|
|
|
315
|
|
|
|
|
|
|
} # comment |
316
|
|
|
|
|
|
|
|
317
|
|
|
|
|
|
|
|
318
|
|
|
|
|
|
|
|
319
|
|
|
|
|
|
|
=head2 to_string |
320
|
|
|
|
|
|
|
|
321
|
|
|
|
|
|
|
Title : to_string() |
322
|
|
|
|
|
|
|
Usage : print $co->to_string(); |
323
|
|
|
|
|
|
|
Function: To string method for Correlate objects. |
324
|
|
|
|
|
|
|
Returns : A string representations of this Correlate. |
325
|
|
|
|
|
|
|
Args : |
326
|
|
|
|
|
|
|
|
327
|
|
|
|
|
|
|
=cut |
328
|
|
|
|
|
|
|
|
329
|
|
|
|
|
|
|
sub to_string { |
330
|
|
|
|
|
|
|
|
331
|
1
|
|
|
1
|
1
|
525
|
my ( $self ) = @_; |
332
|
|
|
|
|
|
|
|
333
|
1
|
|
|
|
|
4
|
my $s = ""; |
334
|
|
|
|
|
|
|
|
335
|
1
|
|
|
|
|
3
|
$s .= "-- Name:\n"; |
336
|
1
|
|
|
|
|
4
|
$s .= $self->name()."\n"; |
337
|
1
|
|
|
|
|
2
|
$s .= "-- Description:\n"; |
338
|
1
|
|
|
|
|
4
|
$s .= $self->description()."\n"; |
339
|
1
|
|
|
|
|
3
|
$s .= "-- Species:\n"; |
340
|
1
|
|
|
|
|
4
|
$s .= $self->species()->binomial()."\n"; |
341
|
1
|
|
|
|
|
2
|
$s .= "-- Type of correlation:\n"; |
342
|
1
|
|
|
|
|
3
|
$s .= $self->type()."\n"; |
343
|
1
|
|
|
|
|
2
|
$s .= "-- Comment:\n"; |
344
|
1
|
|
|
|
|
3
|
$s .= $self->comment(); |
345
|
|
|
|
|
|
|
|
346
|
1
|
|
|
|
|
5
|
return $s; |
347
|
|
|
|
|
|
|
|
348
|
|
|
|
|
|
|
} # to_string |
349
|
|
|
|
|
|
|
|
350
|
|
|
|
|
|
|
|
351
|
|
|
|
|
|
|
|
352
|
|
|
|
|
|
|
|
353
|
|
|
|
|
|
|
# Title : _check_ref_type |
354
|
|
|
|
|
|
|
# Function: Checks for the correct type. |
355
|
|
|
|
|
|
|
# Returns : |
356
|
|
|
|
|
|
|
# Args : The value to be checked, the expected class. |
357
|
|
|
|
|
|
|
sub _check_ref_type { |
358
|
11
|
|
|
11
|
|
23
|
my ( $self, $value, $expected_class ) = @_; |
359
|
|
|
|
|
|
|
|
360
|
11
|
50
|
|
|
|
74
|
if ( ! defined( $value ) ) { |
|
|
50
|
|
|
|
|
|
|
|
50
|
|
|
|
|
|
361
|
0
|
|
|
|
|
|
$self->throw( ( caller( 1 ) )[ 3 ] .": Found [undef" |
362
|
|
|
|
|
|
|
."] where [$expected_class] expected" ); |
363
|
|
|
|
|
|
|
} |
364
|
|
|
|
|
|
|
elsif ( ! ref( $value ) ) { |
365
|
0
|
|
|
|
|
|
$self->throw( ( caller( 1 ) )[ 3 ] .": Found scalar" |
366
|
|
|
|
|
|
|
." where [$expected_class] expected" ); |
367
|
|
|
|
|
|
|
} |
368
|
|
|
|
|
|
|
elsif ( ! $value->isa( $expected_class ) ) { |
369
|
0
|
|
|
|
|
|
$self->throw( ( caller( 1 ) )[ 3 ] .": Found [". ref( $value ) |
370
|
|
|
|
|
|
|
."] where [$expected_class] expected" ); |
371
|
|
|
|
|
|
|
} |
372
|
|
|
|
|
|
|
} # _check_ref_type |
373
|
|
|
|
|
|
|
|
374
|
|
|
|
|
|
|
|
375
|
|
|
|
|
|
|
|
376
|
|
|
|
|
|
|
1; |