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# BioPerl module for Bio::Tree::AlleleNode |
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# |
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# Please direct questions and support issues to |
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# |
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# Cared for by Jason Stajich |
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# |
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# Copyright Jason Stajich |
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# |
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# You may distribute this module under the same terms as perl itself |
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# POD documentation - main docs before the code |
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=head1 NAME |
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Bio::Tree::AlleleNode - A Node with Alleles attached |
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=head1 SYNOPSIS |
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use Bio::Tree::AlleleNode; |
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=head1 DESCRIPTION |
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AlleleNodes are basic Ls with the added ability to |
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add Genotypes alleles as defined by the L |
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interface. Genotypes are defined by the L |
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interface, you will probably want to use the L |
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implementation. |
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This is implemented via containment to avoid multiple inheritance |
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problems. Their is a L object which handles |
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the L interface, and is accessible via the |
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L method. |
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=head1 FEEDBACK |
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=head2 Mailing Lists |
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User feedback is an integral part of the evolution of this and other |
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Bioperl modules. Send your comments and suggestions preferably to |
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the Bioperl mailing list. Your participation is much appreciated. |
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bioperl-l@bioperl.org - General discussion |
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http://bioperl.org/wiki/Mailing_lists - About the mailing lists |
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=head2 Support |
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Please direct usage questions or support issues to the mailing list: |
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I |
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rather than to the module maintainer directly. Many experienced and |
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reponsive experts will be able look at the problem and quickly |
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address it. Please include a thorough description of the problem |
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with code and data examples if at all possible. |
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=head2 Reporting Bugs |
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Report bugs to the Bioperl bug tracking system to help us keep track |
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of the bugs and their resolution. Bug reports can be submitted via the |
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web: |
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https://github.com/bioperl/bioperl-live/issues |
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=head1 AUTHOR - Jason Stajich |
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Email jason-at-bioperl-dot-org |
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=head1 APPENDIX |
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The rest of the documentation details each of the object methods. |
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Internal methods are usually preceded with a _ |
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=head1 HISTORY |
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This module was re-written to be a combination of |
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L and L primarily for use in |
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L simulations. |
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=cut |
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# Let the code begin... |
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package Bio::Tree::AlleleNode; |
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use vars qw($UIDCOUNTER); |
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use strict; |
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BEGIN { $UIDCOUNTER = 1 } |
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use Bio::PopGen::Individual; |
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use Bio::PopGen::Genotype; |
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use base qw(Bio::Tree::Node Bio::PopGen::IndividualI); |
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=head2 new |
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Title : new |
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Usage : my $obj = Bio::Tree::AlleleNode->new(); |
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Function: Builds a new Bio::Tree::AlleleNode() object |
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Returns : an instance of Bio::Tree::AlleleNode |
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Args : -unique_id => $id, |
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-genotypes => \@genotypes |
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-left => pointer to Left descendent (optional) |
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-right => pointer to Right descenent (optional) |
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-branch_length => branch length [integer] (optional) |
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-bootstrap => value bootstrap value (string) |
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-description => description of node |
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-id => human readable (unique) id for node |
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Should NOT contain the characters |
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'();:' |
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=cut |
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sub new { |
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my($class,@args) = @_; |
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my $self = $class->SUPER::new(@args); |
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$self->individual( Bio::PopGen::Individual->new(@args)); |
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return $self; |
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} |
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=head2 individual |
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Title : individual |
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Usage : $obj->individual($newval) |
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Function: Get/Set Access to the underlying individual object |
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Returns : L object |
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Args : on set, new value (L) |
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=cut |
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sub individual { |
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my ($self,$newval) = @_; |
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if( defined $newval || ! defined $self->{'individual'} ) { |
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$newval = Bio::PopGen::Individual->new() unless defined $newval; |
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$self->{'individual'} = $newval; |
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} |
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return $self->{'individual'}; |
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} |
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=head2 Bio::PopGen::Individual methods |
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Methods required by L. |
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=head2 unique_id |
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Title : unique_id |
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Usage : my $id = $individual->unique_id |
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Function: Unique Identifier |
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Returns : string representing unique identifier |
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Args : string |
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=cut |
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sub unique_id{ |
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$self->individual->unique_id(@_); |
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} |
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=head2 num_of_results |
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Title : num_of_results |
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Usage : my $count = $person->num_results; |
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Function: returns the count of the number of Results for a person |
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Returns : integer |
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Args : none |
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=cut |
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sub num_of_results { |
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my $self = shift; |
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$self->individual->num_of_results(@_); |
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} |
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=head2 add_Genotype |
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Title : add_Genotype |
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Usage : $individual->add_Genotype |
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Function: add a genotype value, only a single genotype |
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may be associated |
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Returns : count of the number of genotypes associated with this individual |
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Args : @genotypes - Bio::PopGen::GenotypeI object(s) containing |
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alleles plus a marker name |
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=cut |
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sub add_Genotype { |
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my $self = shift; |
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$self->individual->add_Genotype(@_); |
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} |
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=head2 reset_Genotypes |
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Title : reset_Genotypes |
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Usage : $individual->reset_Genotypes; |
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Function: Reset the genotypes stored for this individual |
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Returns : none |
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Args : none |
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=cut |
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sub reset_Genotypes{ |
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my $self = shift; |
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$self->individual->reset_Genotypes(@_); |
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} |
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=head2 remove_Genotype |
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Title : remove_Genotype |
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Usage : $individual->remove_Genotype(@names) |
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Function: Removes the genotypes for the requested markers |
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Returns : none |
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Args : Names of markers |
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=cut |
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sub remove_Genotype{ |
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my $self = shift; |
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$self->individual->remove_Genotype(@_); |
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} |
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=head2 get_Genotypes |
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Title : get_Genotypes |
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Usage : my @genotypes = $ind->get_Genotypes(-marker => $markername); |
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Function: Get the genotypes for an individual, based on a criteria |
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Returns : Array of genotypes |
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Args : either none (return all genotypes) or |
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-marker => name of marker to return (exact match, case matters) |
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236
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=cut |
237
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238
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sub get_Genotypes{ |
239
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2048
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2048
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1
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2043
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my $self = shift; |
240
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2048
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2060
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$self->individual->get_Genotypes(@_); |
241
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} |
242
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243
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=head2 has_Marker |
244
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245
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Title : has_Marker |
246
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Usage : if( $ind->has_Marker($name) ) {} |
247
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Function: Boolean test to see if an Individual has a genotype |
248
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for a specific marker |
249
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Returns : Boolean (true or false) |
250
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Args : String representing a marker name |
251
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252
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253
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=cut |
254
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255
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sub has_Marker{ |
256
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900
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900
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1
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665
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my $self = shift; |
257
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900
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918
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$self->individual->has_Marker(@_); |
258
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} |
259
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260
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=head2 get_marker_names |
261
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262
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Title : get_marker_names |
263
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Usage : my @names = $individual->get_marker_names; |
264
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Function: Returns the list of known marker names |
265
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Returns : List of strings |
266
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Args : none |
267
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268
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269
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=cut |
270
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271
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sub get_marker_names{ |
272
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5
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5
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1
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10
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my $self = shift; |
273
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5
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13
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$self->individual->get_marker_names(@_); |
274
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} |
275
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276
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=head2 Bio::Tree::Node methods |
277
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278
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Methods inherited from L. |
279
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280
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281
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=head2 add_Descendent |
282
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283
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Title : add_Descendent |
284
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Usage : $node->add_Descendent($node); |
285
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Function: Adds a descendent to a node |
286
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Returns : number of current descendents for this node |
287
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Args : Bio::Node::NodeI |
288
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boolean flag, true if you want to ignore the fact that you are |
289
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adding a second node with the same unique id (typically memory |
290
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location reference in this implementation). default is false and |
291
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will throw an error if you try and overwrite an existing node. |
292
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293
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294
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=head2 each_Descendent |
295
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296
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Title : each_Descendent($sortby) |
297
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Usage : my @nodes = $node->each_Descendent; |
298
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Function: all the descendents for this Node (but not their descendents |
299
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|
|
i.e. not a recursive fetchall) |
300
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|
|
Returns : Array of Bio::Tree::NodeI objects |
301
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|
|
Args : $sortby [optional] "height", "creation" or coderef to be used |
302
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|
to sort the order of children nodes. |
303
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304
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305
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|
=head2 remove_Descendent |
306
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307
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|
|
Title : remove_Descendent |
308
|
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|
Usage : $node->remove_Descedent($node_foo); |
309
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|
Function: Removes a specific node from being a Descendent of this node |
310
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|
|
Returns : nothing |
311
|
|
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|
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|
|
Args : An array of Bio::Node::NodeI objects which have be previously |
312
|
|
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|
|
passed to the add_Descendent call of this object. |
313
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314
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315
|
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|
|
=head2 remove_all_Descendents |
316
|
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|
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317
|
|
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|
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|
|
Title : remove_all_Descendents |
318
|
|
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|
|
|
|
Usage : $node->remove_All_Descendents() |
319
|
|
|
|
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|
|
Function: Cleanup the node's reference to descendents and reset |
320
|
|
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|
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|
|
their ancestor pointers to undef, if you don't have a reference |
321
|
|
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|
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|
|
to these objects after this call they will be cleaned up - so |
322
|
|
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|
|
|
|
a get_nodes from the Tree object would be a safe thing to do first |
323
|
|
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|
|
Returns : nothing |
324
|
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|
|
Args : none |
325
|
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326
|
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327
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328
|
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|
|
=head2 get_all_Descendents |
329
|
|
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|
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|
|
|
330
|
|
|
|
|
|
|
Title : get_all_Descendents |
331
|
|
|
|
|
|
|
Usage : my @nodes = $node->get_all_Descendents; |
332
|
|
|
|
|
|
|
Function: Recursively fetch all the nodes and their descendents |
333
|
|
|
|
|
|
|
*NOTE* This is different from each_Descendent |
334
|
|
|
|
|
|
|
Returns : Array or Bio::Tree::NodeI objects |
335
|
|
|
|
|
|
|
Args : none |
336
|
|
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|
|
|
|
|
337
|
|
|
|
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|
|
=cut |
338
|
|
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|
|
|
|
|
339
|
|
|
|
|
|
|
# implemented in the interface |
340
|
|
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|
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341
|
|
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|
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|
|
=head2 ancestor |
342
|
|
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|
|
|
|
|
343
|
|
|
|
|
|
|
Title : ancestor |
344
|
|
|
|
|
|
|
Usage : $obj->ancestor($newval) |
345
|
|
|
|
|
|
|
Function: Set the Ancestor |
346
|
|
|
|
|
|
|
Returns : value of ancestor |
347
|
|
|
|
|
|
|
Args : newvalue (optional) |
348
|
|
|
|
|
|
|
|
349
|
|
|
|
|
|
|
|
350
|
|
|
|
|
|
|
=head2 branch_length |
351
|
|
|
|
|
|
|
|
352
|
|
|
|
|
|
|
Title : branch_length |
353
|
|
|
|
|
|
|
Usage : $obj->branch_length() |
354
|
|
|
|
|
|
|
Function: Get/Set the branch length |
355
|
|
|
|
|
|
|
Returns : value of branch_length |
356
|
|
|
|
|
|
|
Args : newvalue (optional) |
357
|
|
|
|
|
|
|
|
358
|
|
|
|
|
|
|
|
359
|
|
|
|
|
|
|
=head2 bootstrap |
360
|
|
|
|
|
|
|
|
361
|
|
|
|
|
|
|
Title : bootstrap |
362
|
|
|
|
|
|
|
Usage : $obj->bootstrap($newval) |
363
|
|
|
|
|
|
|
Function: Get/Set the bootstrap value |
364
|
|
|
|
|
|
|
Returns : value of bootstrap |
365
|
|
|
|
|
|
|
Args : newvalue (optional) |
366
|
|
|
|
|
|
|
|
367
|
|
|
|
|
|
|
|
368
|
|
|
|
|
|
|
=head2 description |
369
|
|
|
|
|
|
|
|
370
|
|
|
|
|
|
|
Title : description |
371
|
|
|
|
|
|
|
Usage : $obj->description($newval) |
372
|
|
|
|
|
|
|
Function: Get/Set the description string |
373
|
|
|
|
|
|
|
Returns : value of description |
374
|
|
|
|
|
|
|
Args : newvalue (optional) |
375
|
|
|
|
|
|
|
|
376
|
|
|
|
|
|
|
|
377
|
|
|
|
|
|
|
=head2 id |
378
|
|
|
|
|
|
|
|
379
|
|
|
|
|
|
|
Title : id |
380
|
|
|
|
|
|
|
Usage : $obj->id($newval) |
381
|
|
|
|
|
|
|
Function: The human readable identifier for the node |
382
|
|
|
|
|
|
|
Returns : value of human readable id |
383
|
|
|
|
|
|
|
Args : newvalue (optional) |
384
|
|
|
|
|
|
|
Note : id cannot contain the chracters '();:' |
385
|
|
|
|
|
|
|
|
386
|
|
|
|
|
|
|
"A name can be any string of printable characters except blanks, |
387
|
|
|
|
|
|
|
colons, semicolons, parentheses, and square brackets. Because you may |
388
|
|
|
|
|
|
|
want to include a blank in a name, it is assumed that an underscore |
389
|
|
|
|
|
|
|
character ("_") stands for a blank; any of these in a name will be |
390
|
|
|
|
|
|
|
converted to a blank when it is read in." |
391
|
|
|
|
|
|
|
|
392
|
|
|
|
|
|
|
from L |
393
|
|
|
|
|
|
|
|
394
|
|
|
|
|
|
|
=cut |
395
|
|
|
|
|
|
|
|
396
|
|
|
|
|
|
|
=head2 internal_id |
397
|
|
|
|
|
|
|
|
398
|
|
|
|
|
|
|
Title : internal_id |
399
|
|
|
|
|
|
|
Usage : my $internalid = $node->internal_id |
400
|
|
|
|
|
|
|
Function: Returns the internal unique id for this Node |
401
|
|
|
|
|
|
|
(a monotonically increasing number for this in-memory implementation |
402
|
|
|
|
|
|
|
but could be a database determined unique id in other |
403
|
|
|
|
|
|
|
implementations) |
404
|
|
|
|
|
|
|
Returns : unique id |
405
|
|
|
|
|
|
|
Args : none |
406
|
|
|
|
|
|
|
|
407
|
|
|
|
|
|
|
|
408
|
|
|
|
|
|
|
=head2 Bio::Node::NodeI decorated interface implemented |
409
|
|
|
|
|
|
|
|
410
|
|
|
|
|
|
|
The following methods are implemented by L decorated |
411
|
|
|
|
|
|
|
interface. |
412
|
|
|
|
|
|
|
|
413
|
|
|
|
|
|
|
=head2 is_Leaf |
414
|
|
|
|
|
|
|
|
415
|
|
|
|
|
|
|
Title : is_Leaf |
416
|
|
|
|
|
|
|
Usage : if( $node->is_Leaf ) |
417
|
|
|
|
|
|
|
Function: Get Leaf status |
418
|
|
|
|
|
|
|
Returns : boolean |
419
|
|
|
|
|
|
|
Args : none |
420
|
|
|
|
|
|
|
|
421
|
|
|
|
|
|
|
=cut |
422
|
|
|
|
|
|
|
|
423
|
|
|
|
|
|
|
=head2 to_string |
424
|
|
|
|
|
|
|
|
425
|
|
|
|
|
|
|
Title : to_string |
426
|
|
|
|
|
|
|
Usage : my $str = $node->to_string() |
427
|
|
|
|
|
|
|
Function: For debugging, provide a node as a string |
428
|
|
|
|
|
|
|
Returns : string |
429
|
|
|
|
|
|
|
Args : none |
430
|
|
|
|
|
|
|
|
431
|
|
|
|
|
|
|
=head2 height |
432
|
|
|
|
|
|
|
|
433
|
|
|
|
|
|
|
Title : height |
434
|
|
|
|
|
|
|
Usage : my $len = $node->height |
435
|
|
|
|
|
|
|
Function: Returns the height of the tree starting at this |
436
|
|
|
|
|
|
|
node. Height is the maximum branchlength. |
437
|
|
|
|
|
|
|
Returns : The longest length (weighting branches with branch_length) to a leaf |
438
|
|
|
|
|
|
|
Args : none |
439
|
|
|
|
|
|
|
|
440
|
|
|
|
|
|
|
=head2 invalidate_height |
441
|
|
|
|
|
|
|
|
442
|
|
|
|
|
|
|
Title : invalidate_height |
443
|
|
|
|
|
|
|
Usage : private helper method |
444
|
|
|
|
|
|
|
Function: Invalidate our cached value of the node's height in the tree |
445
|
|
|
|
|
|
|
Returns : nothing |
446
|
|
|
|
|
|
|
Args : none |
447
|
|
|
|
|
|
|
|
448
|
|
|
|
|
|
|
=cut |
449
|
|
|
|
|
|
|
|
450
|
|
|
|
|
|
|
#' |
451
|
|
|
|
|
|
|
|
452
|
|
|
|
|
|
|
=head2 add_tag_value |
453
|
|
|
|
|
|
|
|
454
|
|
|
|
|
|
|
Title : add_tag_value |
455
|
|
|
|
|
|
|
Usage : $node->add_tag_value($tag,$value) |
456
|
|
|
|
|
|
|
Function: Adds a tag value to a node |
457
|
|
|
|
|
|
|
Returns : number of values stored for this tag |
458
|
|
|
|
|
|
|
Args : $tag - tag name |
459
|
|
|
|
|
|
|
$value - value to store for the tag |
460
|
|
|
|
|
|
|
|
461
|
|
|
|
|
|
|
|
462
|
|
|
|
|
|
|
=head2 remove_tag |
463
|
|
|
|
|
|
|
|
464
|
|
|
|
|
|
|
Title : remove_tag |
465
|
|
|
|
|
|
|
Usage : $node->remove_tag($tag) |
466
|
|
|
|
|
|
|
Function: Remove the tag and all values for this tag |
467
|
|
|
|
|
|
|
Returns : boolean representing success (0 if tag does not exist) |
468
|
|
|
|
|
|
|
Args : $tag - tagname to remove |
469
|
|
|
|
|
|
|
|
470
|
|
|
|
|
|
|
|
471
|
|
|
|
|
|
|
|
472
|
|
|
|
|
|
|
=head2 remove_all_tags |
473
|
|
|
|
|
|
|
|
474
|
|
|
|
|
|
|
Title : remove_all_tags |
475
|
|
|
|
|
|
|
Usage : $node->remove_all_tags() |
476
|
|
|
|
|
|
|
Function: Removes all tags |
477
|
|
|
|
|
|
|
Returns : None |
478
|
|
|
|
|
|
|
Args : None |
479
|
|
|
|
|
|
|
|
480
|
|
|
|
|
|
|
|
481
|
|
|
|
|
|
|
|
482
|
|
|
|
|
|
|
=head2 get_all_tags |
483
|
|
|
|
|
|
|
|
484
|
|
|
|
|
|
|
Title : get_all_tags |
485
|
|
|
|
|
|
|
Usage : my @tags = $node->get_all_tags() |
486
|
|
|
|
|
|
|
Function: Gets all the tag names for this Node |
487
|
|
|
|
|
|
|
Returns : Array of tagnames |
488
|
|
|
|
|
|
|
Args : None |
489
|
|
|
|
|
|
|
|
490
|
|
|
|
|
|
|
|
491
|
|
|
|
|
|
|
=head2 get_tag_values |
492
|
|
|
|
|
|
|
|
493
|
|
|
|
|
|
|
Title : get_tag_values |
494
|
|
|
|
|
|
|
Usage : my @values = $node->get_tag_value($tag) |
495
|
|
|
|
|
|
|
Function: Gets the values for given tag ($tag) |
496
|
|
|
|
|
|
|
Returns : Array of values or empty list if tag does not exist |
497
|
|
|
|
|
|
|
Args : $tag - tag name |
498
|
|
|
|
|
|
|
|
499
|
|
|
|
|
|
|
|
500
|
|
|
|
|
|
|
=head2 has_tag |
501
|
|
|
|
|
|
|
|
502
|
|
|
|
|
|
|
Title : has_tag |
503
|
|
|
|
|
|
|
Usage : $node->has_tag($tag) |
504
|
|
|
|
|
|
|
Function: Boolean test if tag exists in the Node |
505
|
|
|
|
|
|
|
Returns : Boolean |
506
|
|
|
|
|
|
|
Args : $tag - tagname |
507
|
|
|
|
|
|
|
|
508
|
|
|
|
|
|
|
|
509
|
|
|
|
|
|
|
=cut |
510
|
|
|
|
|
|
|
|
511
|
|
|
|
|
|
|
|
512
|
|
|
|
|
|
|
1; |