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=head1 NAME |
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Bio::Util::AA - Basic Amino Acid utilities |
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=head1 SYNOPSES |
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use Bio::Util::AA qw(:all) |
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=head1 DESCRIPTION |
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Provides a set of functions and predefined variables which |
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are handy when working with Amino Acids. |
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=cut |
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package Bio::Util::AA; |
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use strict; |
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use warnings; |
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use version; our $VERSION = qv('0.1.6'); |
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use Exporter 'import'; |
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our @EXPORT_OK = qw( |
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%ambiguous_forward |
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%ambiguous_map |
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%aa_abbrev |
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$aas |
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$aa_match |
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$aa_fail |
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$strict_aas |
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$strict_match |
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$strict_fail |
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$ambigs |
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$ambig_match |
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$ambig_fail |
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); |
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our %EXPORT_TAGS = ( |
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all => \@EXPORT_OK, |
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funcs => [qw()] |
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); |
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=head1 VARIABLES |
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=cut |
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=head2 AMBIGUOUS MAPPINGS |
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Two ambiguous mapping hashes. One maps from the amino acid |
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forward to the possible ambiguous amino acid, and one is a |
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map of what each ambiguous amino acid means. |
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=cut |
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our %ambiguous_forward = ( |
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A => 'B', |
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B => 'B', |
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D => 'B', |
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I => 'J', |
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J => 'J', |
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L => 'J', |
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E => 'Z', |
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Q => 'Z', |
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Z => 'Z' |
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); |
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our %ambiguous_map = ( |
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B => [ 'A', 'D' ], |
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J => [ 'I', 'L' ], |
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Z => [ 'E', 'Q' ] |
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); |
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=head2 %aa_abbrev |
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Hash from one letter code for amino acids to the three |
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letter abbreviations. Includes ambiguous amino acids as well |
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as selenocysteine and pyrrolysine. |
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=cut |
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our %aa_abbrev = ( |
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A => 'Ala', |
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B => 'Asx', |
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C => 'Cys', |
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D => 'Asp', |
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E => 'Glu', |
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F => 'Phe', |
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G => 'Gly', |
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H => 'His', |
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I => 'Ile', |
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J => 'Xle', |
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K => 'Lys', |
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L => 'Leu', |
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M => 'Met', |
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N => 'Asn', |
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O => 'Pyl', |
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P => 'Pro', |
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Q => 'Gln', |
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R => 'Arg', |
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S => 'Ser', |
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T => 'Thr', |
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U => 'Sec', |
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V => 'Val', |
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W => 'Trp', |
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X => 'Xaa', |
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Y => 'Tyr', |
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Z => 'Glx' |
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); |
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113
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=head2 BASIC VARIABLES |
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115
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Basic useful amino acid variables. A list of valid |
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characters for amino acids, a stricter list containing just |
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the 20 common ones and *, and another list containing the |
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ambiguous amino acids. Also associated precompiled |
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regular expressions. |
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121
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=cut |
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123
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our $aas = '*ABCDEFGHIJKLMNOPQRSTUVWXYZ'; |
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our $aa_match = qr/[$aas]/i; |
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our $aa_fail = qr/[^$aas]/i; |
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our $strict_aas = '*ACDEFGHIKLMNPQRSTVWXY'; |
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our $strict_match = qr/[$strict_aas]/i; |
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our $strict_fail = qr/[^$strict_aas]/i; |
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our $ambigs = 'BJZ'; |
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our $ambig_match = qr/[$ambigs]/i; |
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our $ambig_fail = qr/[^$ambigs]/i; |
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135
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1; |
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137
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=head1 AUTHOR |
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Kevin Galinsky, |
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=head1 COPYRIGHT AND LICENSE |
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Copyright (c) 2010-2011, Broad Institute. |
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Copyright (c) 2008-2009, J. Craig Venter Institute. |
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This program is free software; you can redistribute it and/or modify it |
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under the same terms as Perl itself. |
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=cut |