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| 1 |  |  |  |  |  |  | package Bio::DOOP::Util::Filt; | 
| 2 |  |  |  |  |  |  |  | 
| 3 | 1 |  |  | 1 |  | 7 | use strict; | 
|  | 1 |  |  |  |  | 2 |  | 
|  | 1 |  |  |  |  | 50 |  | 
| 4 | 1 |  |  | 1 |  | 7 | use warnings; | 
|  | 1 |  |  |  |  | 2 |  | 
|  | 1 |  |  |  |  | 635 |  | 
| 5 |  |  |  |  |  |  |  | 
| 6 |  |  |  |  |  |  | =head1 NAME | 
| 7 |  |  |  |  |  |  |  | 
| 8 |  |  |  |  |  |  | Bio::DOOP::Util::Filt - Filter a cluster list | 
| 9 |  |  |  |  |  |  |  | 
| 10 |  |  |  |  |  |  | =head1 VERSION | 
| 11 |  |  |  |  |  |  |  | 
| 12 |  |  |  |  |  |  | Version 0.3 | 
| 13 |  |  |  |  |  |  |  | 
| 14 |  |  |  |  |  |  | =cut | 
| 15 |  |  |  |  |  |  |  | 
| 16 |  |  |  |  |  |  | our $VERSION = '0.3'; | 
| 17 |  |  |  |  |  |  |  | 
| 18 |  |  |  |  |  |  | =head1 SYNOPSIS | 
| 19 |  |  |  |  |  |  |  | 
| 20 |  |  |  |  |  |  | use Bio::DOOP::DOOP; | 
| 21 |  |  |  |  |  |  |  | 
| 22 |  |  |  |  |  |  | @list = ("81001020","81001110","81001200","80100006"); | 
| 23 |  |  |  |  |  |  | $db   = Bio::DOOP::DBSQL->connect("username","passwd","doop-chordate-1_4","localhost"); | 
| 24 |  |  |  |  |  |  | $filt = Bio::DOOP::Util::Filt->new_by_list($db,\@list,500); | 
| 25 |  |  |  |  |  |  |  | 
| 26 |  |  |  |  |  |  | @res = @{$filt->filt_by_goid("0046872")}; | 
| 27 |  |  |  |  |  |  | for(@res){ | 
| 28 |  |  |  |  |  |  | print $_->get_cluster_id,"\n"; | 
| 29 |  |  |  |  |  |  | } | 
| 30 |  |  |  |  |  |  |  | 
| 31 |  |  |  |  |  |  | =head1 DESCRIPTION | 
| 32 |  |  |  |  |  |  |  | 
| 33 |  |  |  |  |  |  | This object filters a clusterlist. It is useful to find a smaller cluster set from a | 
| 34 |  |  |  |  |  |  | large mofext or fuzznuc search result. | 
| 35 |  |  |  |  |  |  |  | 
| 36 |  |  |  |  |  |  | =head1 AUTHORS | 
| 37 |  |  |  |  |  |  |  | 
| 38 |  |  |  |  |  |  | Tibor Nagy, Godollo, Hungary and Endre Sebestyen, Martonvasar, Hungary | 
| 39 |  |  |  |  |  |  |  | 
| 40 |  |  |  |  |  |  | =head1 METHODS | 
| 41 |  |  |  |  |  |  |  | 
| 42 |  |  |  |  |  |  | =head2 new | 
| 43 |  |  |  |  |  |  |  | 
| 44 |  |  |  |  |  |  | Creates a new filter object from a cluster object array. | 
| 45 |  |  |  |  |  |  |  | 
| 46 |  |  |  |  |  |  | =cut | 
| 47 |  |  |  |  |  |  |  | 
| 48 |  |  |  |  |  |  | sub new { | 
| 49 | 0 |  |  | 0 | 1 |  | my $self                 = {}; | 
| 50 | 0 |  |  |  |  |  | my $dummy                = shift; | 
| 51 | 0 |  |  |  |  |  | my $db                   = shift; | 
| 52 | 0 |  |  |  |  |  | my $clarray              = shift; | 
| 53 | 0 |  |  |  |  |  | my $prom                 = shift; | 
| 54 |  |  |  |  |  |  |  | 
| 55 | 0 |  |  |  |  |  | $self->{CLARRAY}         = $clarray; | 
| 56 | 0 |  |  |  |  |  | $self->{DB}              = $db; | 
| 57 | 0 |  |  |  |  |  | $self->{PROM}            = $prom; | 
| 58 |  |  |  |  |  |  |  | 
| 59 | 0 |  |  |  |  |  | bless $self; | 
| 60 | 0 |  |  |  |  |  | return($self); | 
| 61 |  |  |  |  |  |  | } | 
| 62 |  |  |  |  |  |  |  | 
| 63 |  |  |  |  |  |  | =head2 new_by_list | 
| 64 |  |  |  |  |  |  |  | 
| 65 |  |  |  |  |  |  | Creates a new filter class from a cluster id array. | 
| 66 |  |  |  |  |  |  |  | 
| 67 |  |  |  |  |  |  | =cut | 
| 68 |  |  |  |  |  |  |  | 
| 69 |  |  |  |  |  |  | sub new_by_list { | 
| 70 | 0 |  |  | 0 | 1 |  | my $self                 = {}; | 
| 71 | 0 |  |  |  |  |  | my $dummy                = shift; | 
| 72 | 0 |  |  |  |  |  | my $db                   = shift; | 
| 73 | 0 |  |  |  |  |  | my $clarray_id           = shift; | 
| 74 | 0 |  |  |  |  |  | my $prom                 = shift; | 
| 75 | 0 |  |  |  |  |  | my @clarray; | 
| 76 |  |  |  |  |  |  |  | 
| 77 | 0 |  |  |  |  |  | for my $id (@{$clarray_id}){ | 
|  | 0 |  |  |  |  |  |  | 
| 78 | 0 |  |  |  |  |  | my $cl = Bio::DOOP::Cluster->new($db,$id,$prom); | 
| 79 | 0 | 0 |  |  |  |  | if ($cl == -1){ | 
| 80 | 0 |  |  |  |  |  | next; | 
| 81 |  |  |  |  |  |  | } | 
| 82 | 0 |  |  |  |  |  | push @clarray,$cl; | 
| 83 |  |  |  |  |  |  | } | 
| 84 |  |  |  |  |  |  |  | 
| 85 | 0 |  |  |  |  |  | $self->{CLARRAY}         = \@clarray; | 
| 86 | 0 |  |  |  |  |  | $self->{DB}              = $db; | 
| 87 | 0 |  |  |  |  |  | $self->{PROM}            = $prom; | 
| 88 |  |  |  |  |  |  |  | 
| 89 | 0 |  |  |  |  |  | bless $self; | 
| 90 | 0 |  |  |  |  |  | return($self); | 
| 91 |  |  |  |  |  |  | } | 
| 92 |  |  |  |  |  |  |  | 
| 93 |  |  |  |  |  |  | =head2 new_by_id | 
| 94 |  |  |  |  |  |  |  | 
| 95 |  |  |  |  |  |  | Creates a new filter class from a cluster primary id array. | 
| 96 |  |  |  |  |  |  |  | 
| 97 |  |  |  |  |  |  | =cut | 
| 98 |  |  |  |  |  |  |  | 
| 99 |  |  |  |  |  |  | sub new_by_id { | 
| 100 | 0 |  |  | 0 | 1 |  | my $self                 = {}; | 
| 101 | 0 |  |  |  |  |  | my $dummy                = shift; | 
| 102 | 0 |  |  |  |  |  | my $db                   = shift; | 
| 103 | 0 |  |  |  |  |  | my $clarray_id           = shift; | 
| 104 | 0 |  |  |  |  |  | my @clarray; | 
| 105 |  |  |  |  |  |  |  | 
| 106 | 0 |  |  |  |  |  | for my $id (@{$clarray_id}){ | 
|  | 0 |  |  |  |  |  |  | 
| 107 | 0 |  |  |  |  |  | my $cl = Bio::DOOP::Cluster->new_by_id($db,$id); | 
| 108 | 0 | 0 |  |  |  |  | if ($cl == -1){ | 
| 109 | 0 |  |  |  |  |  | next; | 
| 110 |  |  |  |  |  |  | } | 
| 111 | 0 |  |  |  |  |  | push @clarray,$cl; | 
| 112 |  |  |  |  |  |  | } | 
| 113 |  |  |  |  |  |  |  | 
| 114 | 0 |  |  |  |  |  | $self->{CLARRAY}         = \@clarray; | 
| 115 | 0 |  |  |  |  |  | $self->{DB}              = $db; | 
| 116 |  |  |  |  |  |  |  | 
| 117 | 0 |  |  |  |  |  | bless $self; | 
| 118 | 0 |  |  |  |  |  | return($self); | 
| 119 |  |  |  |  |  |  | } | 
| 120 |  |  |  |  |  |  |  | 
| 121 |  |  |  |  |  |  | =head2 filt_by_goid | 
| 122 |  |  |  |  |  |  |  | 
| 123 |  |  |  |  |  |  | Filter the cluster list by GO ids. | 
| 124 |  |  |  |  |  |  |  | 
| 125 |  |  |  |  |  |  | @filtered = @{$filt->filt_by_goid("0006523")}; | 
| 126 |  |  |  |  |  |  |  | 
| 127 |  |  |  |  |  |  | =cut | 
| 128 |  |  |  |  |  |  |  | 
| 129 |  |  |  |  |  |  | sub filt_by_goid { | 
| 130 | 0 |  |  | 0 | 1 |  | my $self                 = shift; | 
| 131 | 0 |  |  |  |  |  | my $goid                 = shift; | 
| 132 |  |  |  |  |  |  |  | 
| 133 | 0 |  |  |  |  |  | my @cl = @{$self->{CLARRAY}}; | 
|  | 0 |  |  |  |  |  |  | 
| 134 | 0 |  |  |  |  |  | my @ret; | 
| 135 |  |  |  |  |  |  |  | 
| 136 | 0 |  |  |  |  |  | CLUSTER:for my $cl (@cl){ | 
| 137 | 0 |  |  |  |  |  | my @seqs = @{$cl->get_all_seqs}; | 
|  | 0 |  |  |  |  |  |  | 
| 138 | 0 |  |  |  |  |  | for my $seq (@seqs){ | 
| 139 | 0 |  |  |  |  |  | my $goids = $seq->get_xref_value("go_id"); | 
| 140 | 0 | 0 |  |  |  |  | if ($goids == -1){next} | 
|  | 0 |  |  |  |  |  |  | 
| 141 | 0 |  |  |  |  |  | for my $id (@{$goids}){ | 
|  | 0 |  |  |  |  |  |  | 
| 142 | 0 | 0 |  |  |  |  | if ($id eq $goid){ | 
| 143 | 0 |  |  |  |  |  | push @ret,$cl; | 
| 144 | 0 |  |  |  |  |  | next CLUSTER; | 
| 145 |  |  |  |  |  |  | } | 
| 146 |  |  |  |  |  |  | } | 
| 147 |  |  |  |  |  |  | } | 
| 148 |  |  |  |  |  |  | } | 
| 149 |  |  |  |  |  |  |  | 
| 150 | 0 |  |  |  |  |  | return(\@ret); | 
| 151 |  |  |  |  |  |  | } | 
| 152 |  |  |  |  |  |  |  | 
| 153 |  |  |  |  |  |  | 1; |