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package AI::Gene::Sequence; |
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require 5.6.0; |
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use strict; |
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use warnings; |
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BEGIN { |
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use Exporter (); |
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our ($VERSION, @ISA, @EXPORT, @EXPORT_OK, %EXPORT_TAGS); |
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$VERSION = 0.22; |
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@ISA = qw(Exporter); |
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@EXPORT = (); |
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%EXPORT_TAGS = (); |
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@EXPORT_OK = qw(); |
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} |
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our @EXPORT_OK; |
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my ($probs,$mut_keys) = _normalise( { map {$_ => 1} |
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qw(insert remove overwrite |
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duplicate minor major |
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switch shuffle reverse) } ); |
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## |
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# calls mutation method at random |
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# 0: number of mutations to perform |
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# 1: ref to hash of probs to use (otherwise uses default mutations and probs) |
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sub mutate { |
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my $self = shift; |
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my $num_mutates = +$_[0] || 1; |
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my $rt = 0; |
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my ($hr_probs, $muts); |
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if (ref $_[1] eq 'HASH') { # use non standard mutations or probs |
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($hr_probs, $muts) = _normalise($_[1]); |
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} |
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else { # use standard mutations and probs |
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$hr_probs = $probs; |
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$muts = $mut_keys; |
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} |
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MUT_CYCLE: for (1..$num_mutates) { |
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my $rand = rand; |
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foreach my $mutation (@{$muts}) { |
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next unless $rand < $hr_probs->{$mutation}; |
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my $mut = 'mutate_' . $mutation; |
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$rt += $self->$mut(1); |
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next MUT_CYCLE; |
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} |
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} |
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return $rt; |
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} |
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## |
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# creates a normalised and cumulative prob distribution for the |
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# keys of the referenced hash |
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sub _normalise { |
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my $hr = $_[0]; |
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my $h2 = {}; |
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my $muts = [keys %{$hr}]; |
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my $sum = 0; |
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foreach (values %{$hr}) { |
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$sum += $_; |
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} |
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if ($sum <= 0) { |
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die "Cannot randomly mutate with bad probability distribution"; |
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} |
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else { |
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my $cum; |
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@{$h2}{ @{$muts} } = map {$cum +=$_; $cum / $sum} @{$hr}{ @{$muts} }; |
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return ($h2, $muts); |
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} |
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} |
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## |
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# inserts one element into the sequence |
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# 0: number to perform ( or 1) |
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# 1: position to mutate (undef for random) |
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sub mutate_insert { |
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my $self = shift; |
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my $num = +$_[0] || 1; |
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my $rt = 0; |
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for (1..$num) { |
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my $length = length $self->[0]; |
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my $pos = defined($_[1]) ? $_[1] : int rand $length; |
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next if $pos > $length; # further than 1 place after gene |
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my @token = $self->generate_token; |
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my $new = $self->[0]; |
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substr($new, $pos, 0) = $token[0]; |
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next unless $self->valid_gene($new, $pos); |
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$self->[0] = $new; |
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splice @{$self->[1]}, $pos, 0, $token[1]; |
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$rt++; |
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} |
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return $rt; |
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} |
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## |
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# removes element(s) from sequence |
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# 0: number of times to perform |
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# 1: position to affect (undef for rand) |
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# 2: length to affect, undef => 1, 0 => random length |
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sub mutate_remove { |
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my $self = shift; |
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my $num = +$_[0] || 1; |
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my $rt = 0; |
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for (1..$num) { |
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my $length = length $self->[0]; |
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my $len = !defined($_[2]) ? 1 : ($_[2] || int rand $length); |
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next if ($length - $len) <= 0; |
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my $pos = defined($_[1]) ? $_[1] : int rand $length; |
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next if $pos >= $length; # outside of gene |
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my $new = $self->[0]; |
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substr($new, $pos, $len) = ''; |
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next unless $self->valid_gene($new, $pos); |
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$self->[0] = $new; |
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splice @{$self->[1]}, $pos, $len; |
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$rt++; |
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} |
121
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return $rt; |
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} |
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## |
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# copies an element or run of elements into a random place in the gene |
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# 0: number to perform (or 1) |
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# 1: posn to copy from (undef for rand) |
128
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# 2: posn to splice in (undef for rand) |
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# 3: length (undef for 1, 0 for random) |
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sub mutate_duplicate { |
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1
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my $self = shift; |
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my $num = +$_[0] || 1; |
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my $rt = 0; |
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for (1..$num) { |
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my $length = length $self->[0]; |
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100
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my $len = !defined($_[3]) ? 1 : ($_[3] || int rand $length); |
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my $pos1 = defined($_[1]) ? $_[1] : int rand $length; |
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my $pos2 = defined($_[2]) ? $_[2] : int rand $length; |
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my $new = $self->[0]; |
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next if ($pos1 + $len) > $length; |
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next if $pos2 > $length; |
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my $seq = substr($new, $pos1, $len); |
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substr($new, $pos2,0) = $seq; |
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next unless $self->valid_gene($new); |
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$self->[0] = $new; |
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splice @{$self->[1]}, $pos2, 0, @{$self->[1]}[$pos1..($pos1+$len-1)]; |
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148
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$rt++; |
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} |
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return $rt; |
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} |
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153
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## |
154
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# Duplicates a sequence and writes it on top of some other position |
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# 0: num to perform (or 1) |
156
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# 1: pos to get from (undef for rand) |
157
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# 2: pos to start replacement (undef for rand) |
158
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# 3: length to operate on (undef => 1, 0 => rand) |
159
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160
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sub mutate_overwrite { |
161
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1
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my $self = shift; |
162
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my $num = +$_[0] || 1; |
163
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my $rt = 0; |
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165
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for (1..$num) { |
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my $new = $self->[0]; |
167
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my $length = length $self->[0]; |
168
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100
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100
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191
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my $len = !defined($_[3]) ? 1 : ($_[3] || int rand $length); |
169
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100
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102
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my $pos1 = defined($_[1]) ? $_[1] : int rand $length; |
170
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100
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107
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my $pos2 = defined($_[2]) ? $_[2] : int rand $length; |
171
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100
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next if ( ($pos1 + $len) >= $length |
172
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or $pos2 > $length); |
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substr($new, $pos2, $len) = substr($new, $pos1, $len); |
174
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next unless $self->valid_gene($new); |
175
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65
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$self->[0] = $new; |
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splice (@{$self->[1]}, $pos2, $len, |
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177
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@{$self->[1]}[$pos1..($pos1+$len-1)] ); |
178
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89
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$rt++; |
179
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} |
180
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181
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49
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265
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return $rt; |
182
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} |
183
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184
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## |
185
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# Takes a run of tokens and reverses their order, is a noop with 1 item |
186
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# 0: number to perform |
187
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# 1: posn to start from (undef for rand) |
188
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# 2: length (undef=>1, 0=>rand) |
189
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190
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sub mutate_reverse { |
191
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35
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35
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1
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1364
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my $self = shift; |
192
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35
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50
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|
87
|
my $num = +$_[0] || 1; |
193
|
35
|
|
|
|
|
39
|
my $rt = 0; |
194
|
|
|
|
|
|
|
|
195
|
35
|
|
|
|
|
60
|
for (1..$num) { |
196
|
35
|
|
|
|
|
50
|
my $length = length $self->[0]; |
197
|
35
|
|
|
|
|
83
|
my $new = $self->[0]; |
198
|
35
|
100
|
|
|
|
86
|
my $pos = defined($_[1]) ? $_[1] : int rand $length; |
199
|
35
|
100
|
100
|
|
|
143
|
my $len = !defined($_[2]) ? 1 : ($_[2] || int rand $length); |
200
|
|
|
|
|
|
|
|
201
|
35
|
100
|
100
|
|
|
167
|
next if ($pos >= $length |
202
|
|
|
|
|
|
|
or $pos + $len > $length); |
203
|
|
|
|
|
|
|
|
204
|
23
|
|
|
|
|
87
|
my $chunk = reverse split('', substr($new, $pos, $len)); |
205
|
23
|
|
|
|
|
82
|
substr($new, $pos, $len) = join('', $chunk); |
206
|
23
|
50
|
|
|
|
51
|
next unless $self->valid_gene($new); |
207
|
23
|
|
|
|
|
75
|
$self->[0] = $new; |
208
|
23
|
|
|
|
|
50
|
splice (@{$self->[1]}, $pos, $len, |
|
23
|
|
|
|
|
77
|
|
209
|
23
|
|
|
|
|
29
|
reverse( @{$self->[1]}[$pos..($pos+$len-1)] )); |
210
|
23
|
|
|
|
|
106
|
$rt++; |
211
|
|
|
|
|
|
|
} |
212
|
35
|
|
|
|
|
187
|
return $rt; |
213
|
|
|
|
|
|
|
} |
214
|
|
|
|
|
|
|
|
215
|
|
|
|
|
|
|
## |
216
|
|
|
|
|
|
|
# Changes token into one of same type (ie. passes type to generate..) |
217
|
|
|
|
|
|
|
# 0: number to perform |
218
|
|
|
|
|
|
|
# 1: position to affect (undef for rand) |
219
|
|
|
|
|
|
|
|
220
|
|
|
|
|
|
|
sub mutate_minor { |
221
|
41
|
|
|
41
|
1
|
1372
|
my $self = shift; |
222
|
41
|
|
100
|
|
|
133
|
my $num = +$_[0] || 1; |
223
|
41
|
|
|
|
|
43
|
my $rt = 0; |
224
|
41
|
|
|
|
|
71
|
for (1..$num) { |
225
|
41
|
100
|
|
|
|
145
|
my $pos = defined $_[1] ? $_[1] : int rand length $self->[0]; |
226
|
41
|
100
|
|
|
|
97
|
next if $pos >= length($self->[0]); # pos lies outside of gene |
227
|
40
|
|
|
|
|
62
|
my $type = substr($self->[0], $pos, 1); |
228
|
40
|
|
|
|
|
108
|
my @token = $self->generate_token($type, $self->[1][$pos]); |
229
|
|
|
|
|
|
|
# still need to check for niceness, just in case |
230
|
40
|
50
|
|
|
|
362
|
if ($token[0] eq $type) { |
231
|
40
|
|
|
|
|
68
|
$self->[1][$pos] = $token[1]; |
232
|
|
|
|
|
|
|
} |
233
|
|
|
|
|
|
|
else { |
234
|
0
|
|
|
|
|
0
|
my $new = $self->[0]; |
235
|
0
|
|
|
|
|
0
|
substr($new, $pos, 1) = $token[0]; |
236
|
0
|
0
|
|
|
|
0
|
next unless $self->valid_gene($new, $pos); |
237
|
0
|
|
|
|
|
0
|
$self->[0] = $new; |
238
|
0
|
|
|
|
|
0
|
$self->[1][$pos] = $token[1]; |
239
|
|
|
|
|
|
|
} |
240
|
40
|
|
|
|
|
104
|
$rt++; |
241
|
|
|
|
|
|
|
} |
242
|
41
|
|
|
|
|
192
|
return $rt; |
243
|
|
|
|
|
|
|
} |
244
|
|
|
|
|
|
|
|
245
|
|
|
|
|
|
|
## |
246
|
|
|
|
|
|
|
# Changes one token into some other token |
247
|
|
|
|
|
|
|
# 0: number to perform |
248
|
|
|
|
|
|
|
# 1: position to affect (undef for random) |
249
|
|
|
|
|
|
|
|
250
|
|
|
|
|
|
|
sub mutate_major { |
251
|
41
|
|
|
41
|
1
|
2079
|
my $self = shift; |
252
|
41
|
|
100
|
|
|
134
|
my $num = +$_[0] || 1; |
253
|
41
|
|
|
|
|
44
|
my $rt = 0; |
254
|
41
|
|
|
|
|
72
|
for (1..$num) { |
255
|
41
|
100
|
|
|
|
104
|
my $pos = defined $_[1] ? $_[1] : int rand length $self->[0]; |
256
|
41
|
100
|
|
|
|
91
|
next if $pos >= length($self->[0]); # outside of gene |
257
|
40
|
|
|
|
|
87
|
my @token = $self->generate_token(); |
258
|
40
|
|
|
|
|
305
|
my $new = $self->[0]; |
259
|
40
|
|
|
|
|
56
|
substr($new, $pos, 1) = $token[0]; |
260
|
40
|
50
|
|
|
|
86
|
next unless $self->valid_gene($new, $pos); |
261
|
40
|
|
|
|
|
58
|
$self->[0] = $new; |
262
|
40
|
|
|
|
|
53
|
$self->[1][$pos] = $token[1]; |
263
|
40
|
|
|
|
|
109
|
$rt++; |
264
|
|
|
|
|
|
|
} |
265
|
41
|
|
|
|
|
174
|
return $rt; |
266
|
|
|
|
|
|
|
} |
267
|
|
|
|
|
|
|
|
268
|
|
|
|
|
|
|
## |
269
|
|
|
|
|
|
|
# swaps over two sequences within the gene |
270
|
|
|
|
|
|
|
# any sort of oddness can occur if regions overlap |
271
|
|
|
|
|
|
|
# 0: number to perform |
272
|
|
|
|
|
|
|
# 1: start of first sequence (undef for rand) |
273
|
|
|
|
|
|
|
# 2: start of second sequence (undef for rand) |
274
|
|
|
|
|
|
|
# 3: length of first sequence (undef for 1, 0 for rand) |
275
|
|
|
|
|
|
|
# 4: length of second sequence (undef for 1, 0 for rand) |
276
|
|
|
|
|
|
|
|
277
|
|
|
|
|
|
|
sub mutate_switch { |
278
|
41
|
|
|
41
|
1
|
2385
|
my $self = shift; |
279
|
41
|
|
50
|
|
|
310
|
my $num = $_[0] || 1; |
280
|
41
|
|
|
|
|
59
|
my $rt = 0; |
281
|
41
|
|
|
|
|
99
|
for (1..$num) { |
282
|
41
|
|
|
|
|
72
|
my $length = length $self->[0]; |
283
|
41
|
100
|
|
|
|
125
|
my $pos1 = defined $_[1] ? $_[1] : int rand $length; |
284
|
41
|
100
|
|
|
|
90
|
my $pos2 = defined $_[2] ? $_[2] : int rand $length; |
285
|
41
|
100
|
66
|
|
|
510
|
my $len1 = !defined($_[3]) ? 1 : ($_[3] || int rand $length); |
286
|
41
|
100
|
100
|
|
|
429
|
my $len2 = !defined($_[4]) ? 1 : ($_[4] || int rand $length); |
287
|
|
|
|
|
|
|
|
288
|
41
|
|
|
|
|
76
|
my $new = $self->[0]; |
289
|
41
|
100
|
|
|
|
117
|
next if $pos1 == $pos2; |
290
|
38
|
100
|
|
|
|
89
|
if ($pos1 > $pos2) { # ensure $pos1 comes first |
291
|
14
|
|
|
|
|
30
|
($pos1, $pos2) = ($pos2, $pos1); |
292
|
14
|
|
|
|
|
31
|
($len1, $len2) = ($len2, $len1); |
293
|
|
|
|
|
|
|
} |
294
|
38
|
100
|
100
|
|
|
196
|
if ( ($pos1 + $len1) > $pos2 # ensure no overlaps |
|
|
|
66
|
|
|
|
|
295
|
|
|
|
|
|
|
or ($pos2 + $len2) > $length |
296
|
|
|
|
|
|
|
or $pos1 >= $length ) { |
297
|
27
|
|
|
|
|
90
|
next; |
298
|
|
|
|
|
|
|
} |
299
|
11
|
|
|
|
|
35
|
my $chunk1 = substr($new, $pos1, $len1, substr($new, $pos2, $len2,'')); |
300
|
11
|
|
|
|
|
22
|
substr($new,$pos2 -$len1 + $len2,0) = $chunk1; |
301
|
11
|
50
|
|
|
|
28
|
next unless $self->valid_gene($new); |
302
|
11
|
|
|
|
|
28
|
$self->[0]= $new; |
303
|
11
|
|
|
|
|
25
|
my @chunk1 = splice(@{$self->[1]}, $pos1, $len1, |
|
11
|
|
|
|
|
53
|
|
304
|
11
|
|
|
|
|
16
|
splice(@{$self->[1]}, $pos2, $len2) ); |
305
|
11
|
|
|
|
|
21
|
splice @{$self->[1]}, $pos2 + $len2 - $len1,0, @chunk1; |
|
11
|
|
|
|
|
37
|
|
306
|
11
|
|
|
|
|
41
|
$rt++; |
307
|
|
|
|
|
|
|
} |
308
|
41
|
|
|
|
|
305
|
return $rt; |
309
|
|
|
|
|
|
|
} |
310
|
|
|
|
|
|
|
|
311
|
|
|
|
|
|
|
## |
312
|
|
|
|
|
|
|
# takes a sequence, removes it, then inserts it at another position |
313
|
|
|
|
|
|
|
# odd things might occur if posn to replace to lies within area taken from |
314
|
|
|
|
|
|
|
# 0: number to perform |
315
|
|
|
|
|
|
|
# 1: posn to get from (undef for rand) |
316
|
|
|
|
|
|
|
# 2: posn to put (undef for rand) |
317
|
|
|
|
|
|
|
# 3: length of sequence (undef for 1, 0 for rand) |
318
|
|
|
|
|
|
|
|
319
|
|
|
|
|
|
|
sub mutate_shuffle { |
320
|
46
|
|
|
46
|
1
|
2157
|
my $self = shift; |
321
|
46
|
|
50
|
|
|
115
|
my $num = +$_[0] || 1; |
322
|
46
|
|
|
|
|
51
|
my $rt = 0; |
323
|
|
|
|
|
|
|
|
324
|
46
|
|
|
|
|
95
|
for (1..$num) { |
325
|
46
|
|
|
|
|
68
|
my $length = length $self->[0]; |
326
|
46
|
100
|
|
|
|
321
|
my $pos1 = defined($_[1]) ? $_[1] : int rand $length; |
327
|
46
|
100
|
|
|
|
95
|
my $pos2 = defined($_[2]) ? $_[2] : int rand $length; |
328
|
46
|
100
|
100
|
|
|
304
|
my $len = !defined($_[3]) ? 1 : ($_[3] || int rand $length); |
329
|
|
|
|
|
|
|
|
330
|
46
|
|
|
|
|
73
|
my $new = $self->[0]; |
331
|
46
|
100
|
100
|
|
|
321
|
if ($pos1 +$len > $length # outside gene |
|
|
|
100
|
|
|
|
|
|
|
|
66
|
|
|
|
|
332
|
|
|
|
|
|
|
or $pos2 >= $length # outside gene |
333
|
|
|
|
|
|
|
or ($pos2 < ($pos1 + $len) and $pos2 > $pos1)) { # overlap |
334
|
17
|
|
|
|
|
57
|
next; |
335
|
|
|
|
|
|
|
} |
336
|
29
|
100
|
|
|
|
56
|
if ($pos1 < $pos2) { |
337
|
17
|
|
|
|
|
77
|
substr($new, $pos2-$len,0) = substr($new, $pos1, $len, ''); |
338
|
|
|
|
|
|
|
} |
339
|
|
|
|
|
|
|
else { |
340
|
12
|
|
|
|
|
30
|
substr($new, $pos2, 0) = substr($new, $pos1, $len, ''); |
341
|
|
|
|
|
|
|
} |
342
|
29
|
50
|
|
|
|
153
|
next unless $self->valid_gene($new); |
343
|
29
|
|
|
|
|
64
|
$self->[0] = $new; |
344
|
29
|
100
|
|
|
|
52
|
if ($pos1 < $pos2) { |
345
|
17
|
|
|
|
|
32
|
splice (@{$self->[1]}, $pos2-$len, 0, |
|
17
|
|
|
|
|
49
|
|
346
|
17
|
|
|
|
|
21
|
splice(@{$self->[1]}, $pos1, $len) ); |
347
|
|
|
|
|
|
|
} |
348
|
|
|
|
|
|
|
else { |
349
|
12
|
|
|
|
|
26
|
splice(@{$self->[1]}, $pos2, 0, |
|
12
|
|
|
|
|
36
|
|
350
|
12
|
|
|
|
|
12
|
splice(@{$self->[1]}, $pos1, $len) ); |
351
|
|
|
|
|
|
|
} |
352
|
29
|
|
|
|
|
96
|
$rt++; |
353
|
|
|
|
|
|
|
} |
354
|
46
|
|
|
|
|
266
|
return $rt; |
355
|
|
|
|
|
|
|
} |
356
|
|
|
|
|
|
|
|
357
|
|
|
|
|
|
|
# These are intended to be overriden, simple versions are |
358
|
|
|
|
|
|
|
# provided for the sake of testing. |
359
|
|
|
|
|
|
|
|
360
|
|
|
|
|
|
|
# Generates things to make up genes |
361
|
|
|
|
|
|
|
# can be called with a token type to produce, or with none. |
362
|
|
|
|
|
|
|
# if called with a token type, it will also be passed the original |
363
|
|
|
|
|
|
|
# token as the second argument. |
364
|
|
|
|
|
|
|
# should return a two element list of the token type followed by the token itself. |
365
|
|
|
|
|
|
|
|
366
|
|
|
|
|
|
|
sub generate_token { |
367
|
0
|
|
|
0
|
1
|
0
|
my $self = shift; |
368
|
0
|
|
|
|
|
0
|
my $token_type = $_[0]; |
369
|
0
|
|
|
|
|
0
|
my $letter = ('a'..'z')[rand 25]; |
370
|
0
|
0
|
|
|
|
0
|
unless ($token_type) { |
371
|
0
|
|
|
|
|
0
|
return ($letter) x2; |
372
|
|
|
|
|
|
|
} |
373
|
0
|
|
|
|
|
0
|
return ($token_type) x2; |
374
|
|
|
|
|
|
|
} |
375
|
|
|
|
|
|
|
|
376
|
|
|
|
|
|
|
# takes sting of token types to be checked for validity. |
377
|
|
|
|
|
|
|
# If a mutation affects only one place, then the position of the |
378
|
|
|
|
|
|
|
# mutation can be passed as a second argument. |
379
|
242
|
|
|
242
|
1
|
1107
|
sub valid_gene {1} |
380
|
|
|
|
|
|
|
|
381
|
|
|
|
|
|
|
## You might also want to have methods like the following, |
382
|
|
|
|
|
|
|
# they will not be called by the 'sequence' methods. |
383
|
|
|
|
|
|
|
|
384
|
|
|
|
|
|
|
# Default constructor |
385
|
|
|
|
|
|
|
sub new { |
386
|
0
|
|
|
0
|
1
|
0
|
my $gene = ['',[]]; |
387
|
0
|
|
0
|
|
|
0
|
return bless $gene, ref $_[0] || $_[0]; |
388
|
|
|
|
|
|
|
} |
389
|
|
|
|
|
|
|
|
390
|
|
|
|
|
|
|
# remember that clone method may require deep copying depending on |
391
|
|
|
|
|
|
|
# your specific needs |
392
|
|
|
|
|
|
|
|
393
|
|
|
|
|
|
|
sub clone { |
394
|
312
|
|
|
312
|
1
|
21715
|
my $self = shift; |
395
|
312
|
|
|
|
|
1870
|
my $new = [$self->[0]]; |
396
|
312
|
|
|
|
|
422
|
$new->[1] = [@{$self->[1]}]; |
|
312
|
|
|
|
|
1801
|
|
397
|
312
|
|
|
|
|
2265
|
return bless $new, ref $self; |
398
|
|
|
|
|
|
|
} |
399
|
|
|
|
|
|
|
|
400
|
|
|
|
|
|
|
# You need some way to use the gene you've made and mutated, but |
401
|
|
|
|
|
|
|
# this will let you have a look, if it starts being odd. |
402
|
|
|
|
|
|
|
|
403
|
|
|
|
|
|
|
sub render_gene { |
404
|
0
|
|
|
0
|
1
|
|
my $self = shift; |
405
|
0
|
|
|
|
|
|
my $return = "$self\n"; |
406
|
0
|
|
|
|
|
|
$return .= $self->[0] . "\n"; |
407
|
0
|
|
|
|
|
|
$return .= (join ',', @{$self->[1]}). "\n"; |
|
0
|
|
|
|
|
|
|
408
|
0
|
|
|
|
|
|
return $return; |
409
|
|
|
|
|
|
|
} |
410
|
|
|
|
|
|
|
|
411
|
|
|
|
|
|
|
# used for testing |
412
|
|
|
|
|
|
|
|
413
|
|
|
|
|
|
|
sub _test_dump { |
414
|
0
|
|
|
0
|
|
|
my $self = shift; |
415
|
0
|
|
|
|
|
|
my @rt = ($self->[0], join('',@{$self->[1]})); |
|
0
|
|
|
|
|
|
|
416
|
0
|
|
|
|
|
|
return @rt; |
417
|
|
|
|
|
|
|
} |
418
|
|
|
|
|
|
|
1; |
419
|
|
|
|
|
|
|
|
420
|
|
|
|
|
|
|
__END__; |